Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)

The article summarizes years of the authors experience in the diagnosis and treatment of acute poisonings with ethyl alcohol and presents data on the epidemiology of poisoning with ethyl alcohol, as well as modern terminology and systematization of poisoning with alcohols in accordance with the inte...

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Main Authors: V. N. Alexandrovsky, Y. N. Ostapenko, Y. S. Goldfarb, M. M. Potskhveriya, M. V. Kareva
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2019-01-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/537
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author V. N. Alexandrovsky
Y. N. Ostapenko
Y. S. Goldfarb
M. M. Potskhveriya
M. V. Kareva
author_facet V. N. Alexandrovsky
Y. N. Ostapenko
Y. S. Goldfarb
M. M. Potskhveriya
M. V. Kareva
author_sort V. N. Alexandrovsky
collection DOAJ
description The article summarizes years of the authors experience in the diagnosis and treatment of acute poisonings with ethyl alcohol and presents data on the epidemiology of poisoning with ethyl alcohol, as well as modern terminology and systematization of poisoning with alcohols in accordance with the international classification of diseases ICD 10.We analyzed the pharmacokinetics and pharmacodynamics of ethyl alcohol in its toxic effects.The original clinical classification of alcoholic coma, confirmed by electrophysiological studies of the brain is given in the article. We also determined the involvement of deep structures of the brain in the pathogenesis of acute alcohol poisoning.The emergency therapeutic measures in acute alcohol intoxication and its complications, primarily related to accelerated detoxification of the body by forced diuresis are reported. The importance of effective correction of acid-base blood disorders and prevention of acute renal failure is emphasized.The article might provide a more accurate diagnosis of acute alcohol poisoning, accompanied by the development of alcoholic coma, and to improve the quality of treatment of this disease in the intensive care and toxicology departments.
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spelling doaj.art-80a030f1034b4d8f879abe65cb118a882025-03-02T11:06:19ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172019-01-017435736510.23934/2223-9022-2018-7-4-357-365475Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)V. N. Alexandrovsky0Y. N. Ostapenko1Y. S. Goldfarb2M. M. Potskhveriya3M. V. Kareva4Scientific and Practical Toxicology Center of the Federal Medical and Biological Agency of RussiaScientific and Practical Toxicology Center of the Federal Medical and Biological Agency of Russia; N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department; Russian Medical Academy of Continuing Professional EducationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department; Russian Medical Academy of Continuing Professional EducationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department; Russian Medical Academy of Continuing Professional EducationN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department; Russian Medical Academy of Continuing Professional EducationThe article summarizes years of the authors experience in the diagnosis and treatment of acute poisonings with ethyl alcohol and presents data on the epidemiology of poisoning with ethyl alcohol, as well as modern terminology and systematization of poisoning with alcohols in accordance with the international classification of diseases ICD 10.We analyzed the pharmacokinetics and pharmacodynamics of ethyl alcohol in its toxic effects.The original clinical classification of alcoholic coma, confirmed by electrophysiological studies of the brain is given in the article. We also determined the involvement of deep structures of the brain in the pathogenesis of acute alcohol poisoning.The emergency therapeutic measures in acute alcohol intoxication and its complications, primarily related to accelerated detoxification of the body by forced diuresis are reported. The importance of effective correction of acid-base blood disorders and prevention of acute renal failure is emphasized.The article might provide a more accurate diagnosis of acute alcohol poisoning, accompanied by the development of alcoholic coma, and to improve the quality of treatment of this disease in the intensive care and toxicology departments.https://www.jnmp.ru/jour/article/view/537ethyl alcoholacute poisoningdiagnosiselectroencephalographytreatment
spellingShingle V. N. Alexandrovsky
Y. N. Ostapenko
Y. S. Goldfarb
M. M. Potskhveriya
M. V. Kareva
Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
Неотложная медицинская помощь
ethyl alcohol
acute poisoning
diagnosis
electroencephalography
treatment
title Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
title_full Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
title_fullStr Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
title_full_unstemmed Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
title_short Acute Poisoning with Ethyl Alcohol (Alcoholic Coma)
title_sort acute poisoning with ethyl alcohol alcoholic coma
topic ethyl alcohol
acute poisoning
diagnosis
electroencephalography
treatment
url https://www.jnmp.ru/jour/article/view/537
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AT ysgoldfarb acutepoisoningwithethylalcoholalcoholiccoma
AT mmpotskhveriya acutepoisoningwithethylalcoholalcoholiccoma
AT mvkareva acutepoisoningwithethylalcoholalcoholiccoma