Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy
Osteonecrosis of the Femoral Head (ONFH) is a disabling disease affecting up to 30,000 people yearly in the United States alone. Diagnosis and staging of this pathology are both technically and logistically challenging, usually relying on imaging studies. Even anatomopathological studies, considered...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/7/1731 |
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| author | Adrián Cardín-Pereda Daniel García-Sánchez Nuria Terán-Villagrá Ana Alfonso-Fernández Michel Fakkas Carlos Garcés-Zarzalejo Flor María Pérez-Campo |
| author_facet | Adrián Cardín-Pereda Daniel García-Sánchez Nuria Terán-Villagrá Ana Alfonso-Fernández Michel Fakkas Carlos Garcés-Zarzalejo Flor María Pérez-Campo |
| author_sort | Adrián Cardín-Pereda |
| collection | DOAJ |
| description | Osteonecrosis of the Femoral Head (ONFH) is a disabling disease affecting up to 30,000 people yearly in the United States alone. Diagnosis and staging of this pathology are both technically and logistically challenging, usually relying on imaging studies. Even anatomopathological studies, considered the gold standard for identifying ONFH, are not exempt from problems. In addition, the diagnosis is often made by different healthcare specialists, including orthopedic surgeons and radiologists, using different imaging modes, macroscopic features, and stages. Therefore, it is not infrequent to find disagreements between different specialists. The aim of this paper is to clarify the association and accuracy of ONFH diagnosis between healthcare professionals. To this end, femoral head specimens from patients with a diagnosis of ONFH were collected from patients undergoing hip replacement surgery. These samples were later histologically analyzed to establish an ONFH diagnosis. We found that clinico-radiological diagnosis of ONFH evidences a high degree of histological confirmation, thus showing an acceptable diagnostic accuracy. However, when the diagnoses of radiologists and orthopedic surgeons are compared with each other, there is only a moderate agreement. Our results underscore the need to develop an effective diagnosis based on a multidisciplinary approach to enhance currently limited accuracy and reliability. |
| first_indexed | 2024-03-09T03:31:33Z |
| format | Article |
| id | doaj.art-80a0b5b1a9e04c298e7d14ca72cb7240 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T03:31:33Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-80a0b5b1a9e04c298e7d14ca72cb72402023-12-03T14:55:19ZengMDPI AGDiagnostics2075-44182022-07-01127173110.3390/diagnostics12071731Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic AccuracyAdrián Cardín-Pereda0Daniel García-Sánchez1Nuria Terán-Villagrá2Ana Alfonso-Fernández3Michel Fakkas4Carlos Garcés-Zarzalejo5Flor María Pérez-Campo6Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Cantabria-IDIVAL, 39012 Santander, SpainDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Cantabria-IDIVAL, 39012 Santander, SpainServicio de Anatomía Patológica, Hospital UM Valdecilla, Universidad de Cantabria, 39008 Santander, SpainServicio de Traumatología y Ortopedia, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, 39008 Santander, SpainServicio de Traumatología y Ortopedia, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, 39008 Santander, SpainServicio de Traumatología y Ortopedia, Hospital Universitario Marqués de Valdecilla-IDIVAL, Universidad de Cantabria, 39008 Santander, SpainDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Cantabria-IDIVAL, 39012 Santander, SpainOsteonecrosis of the Femoral Head (ONFH) is a disabling disease affecting up to 30,000 people yearly in the United States alone. Diagnosis and staging of this pathology are both technically and logistically challenging, usually relying on imaging studies. Even anatomopathological studies, considered the gold standard for identifying ONFH, are not exempt from problems. In addition, the diagnosis is often made by different healthcare specialists, including orthopedic surgeons and radiologists, using different imaging modes, macroscopic features, and stages. Therefore, it is not infrequent to find disagreements between different specialists. The aim of this paper is to clarify the association and accuracy of ONFH diagnosis between healthcare professionals. To this end, femoral head specimens from patients with a diagnosis of ONFH were collected from patients undergoing hip replacement surgery. These samples were later histologically analyzed to establish an ONFH diagnosis. We found that clinico-radiological diagnosis of ONFH evidences a high degree of histological confirmation, thus showing an acceptable diagnostic accuracy. However, when the diagnoses of radiologists and orthopedic surgeons are compared with each other, there is only a moderate agreement. Our results underscore the need to develop an effective diagnosis based on a multidisciplinary approach to enhance currently limited accuracy and reliability.https://www.mdpi.com/2075-4418/12/7/1731avascular necrosis of the hipdiagnosisradiological testsreproducibilityreliabilityaccuracy |
| spellingShingle | Adrián Cardín-Pereda Daniel García-Sánchez Nuria Terán-Villagrá Ana Alfonso-Fernández Michel Fakkas Carlos Garcés-Zarzalejo Flor María Pérez-Campo Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy Diagnostics avascular necrosis of the hip diagnosis radiological tests reproducibility reliability accuracy |
| title | Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy |
| title_full | Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy |
| title_fullStr | Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy |
| title_full_unstemmed | Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy |
| title_short | Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy |
| title_sort | osteonecrosis of the femoral head a multidisciplinary approach in diagnostic accuracy |
| topic | avascular necrosis of the hip diagnosis radiological tests reproducibility reliability accuracy |
| url | https://www.mdpi.com/2075-4418/12/7/1731 |
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