Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8+T cell infiltration

Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8+T cell infiltration

Abstract Postoperative pain (POP) can promote tumor recurrence and reduce the cancer patient's quality of life. However, POP management has always been separated from tumor treatment in clinical practice, and traditional postoperative analgesia using opioids is still unsatisfactory for patients...

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Bibliographic Details
Main Authors: Mingxu Zhao, Shasha Zhu, Ding Zhang, Chang Zhou, Zhilai Yang, Chunhui Wang, Xuesheng Liu, Jiqian Zhang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Nanobiotechnology
Subjects:
Postoperative pain
Local anesthetic
Tumor recurrence
MHC-I
Hydrogel
Online Access:https://doi.org/10.1186/s12951-023-01803-8

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