Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma

Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma

Abstract Background Clear cell renal cell carcinoma is susceptible to ferroptosis, and immunotherapy is recently recommended as a priority for the initial treatment of metastatic clear cell renal carcinoma. Increased ferroptosis and immune activation can synergistically reinforce each other in killi...

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Bibliographic Details
Main Authors: Yanhua Mou, Jinchun Wu, Yao Zhang, Omar Abdihamid, Chaojun Duan, Bin Li
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Cancer
Subjects:
Ferritinophagy
NCOA4
Clear cell renal carcinoma
Immune cells
Ferroptosis
Online Access:https://doi.org/10.1186/s12885-020-07726-z

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