COX-2 Gene Promoter Methylation in Patients Infected with
Cyclooxygenase (COX) plays a critical role in peptic ulcer development. COX-2 contains CpG islands in promoter area, which suggests possible epigenetic mechanisms of gene silencing. We evaluated COX-2 gene promoter methylation levels in the gastric mucosa of patients with various gastric diseases. D...
Main Authors: | Yosuke Michikawa, Hiroshi Yasuda, Yoshiyuki Watanabe, Ritsuko Oikawa, Yoshichika Ohishi, Tadateru Maehata, Fumio Itoh |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-01-01
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Series: | Clinical Medicine Insights: Gastroenterology |
Online Access: | https://doi.org/10.4137/CGast.S11917 |
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