A case of ureteral myeloid sarcoma post-renal transplantation

Abstract Background Significant attention has been directed toward the high incidence of malignant tumours that occur post-transplantation. However, there are few reports of myeloid sarcomas (MSs) following renal transplantation. Case presentation This case report describes a 26-year-old male patien...

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Main Authors: Liang Ying, Lei Tian, Yuanyuan Xie, Qin Wang, Xiajing Che, Jiayi Yan, Lijing Shen, Honghui Huang, Fangyuan Chen, Ming Zhang, Zhaohui Ni, Shan Mou
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-018-0838-0
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author Liang Ying
Lei Tian
Yuanyuan Xie
Qin Wang
Xiajing Che
Jiayi Yan
Lijing Shen
Honghui Huang
Fangyuan Chen
Ming Zhang
Zhaohui Ni
Shan Mou
author_facet Liang Ying
Lei Tian
Yuanyuan Xie
Qin Wang
Xiajing Che
Jiayi Yan
Lijing Shen
Honghui Huang
Fangyuan Chen
Ming Zhang
Zhaohui Ni
Shan Mou
author_sort Liang Ying
collection DOAJ
description Abstract Background Significant attention has been directed toward the high incidence of malignant tumours that occur post-transplantation. However, there are few reports of myeloid sarcomas (MSs) following renal transplantation. Case presentation This case report describes a 26-year-old male patient who presented with repeatedly high creatinine levels and hydronephrosis six months post-renal transplantation. Surgical pathology revealed ureteral MS; however, the tumour recurred following resection. Bone marrow biopsy indicated that the patient also had acute promyelocytic leukaemia. The tumour was treated with local radiotherapy, and the leukaemia was treated with systemic chemotherapy. The patient’s conditions were satisfactory at the one-year follow-up. Conclusions This report is the first to describe a ureteral MS post-renal transplantation. Our findings suggest that surgical resection combined with radiotherapy and chemotherapy can help control the status of patients with this condition.
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spelling doaj.art-80a3727bcbb842859ab0341eacd6ac892022-12-21T20:36:32ZengBMCBMC Nephrology1471-23692018-02-011911510.1186/s12882-018-0838-0A case of ureteral myeloid sarcoma post-renal transplantationLiang Ying0Lei Tian1Yuanyuan Xie2Qin Wang3Xiajing Che4Jiayi Yan5Lijing Shen6Honghui Huang7Fangyuan Chen8Ming Zhang9Zhaohui Ni10Shan Mou11Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Hematology, Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Hematology, Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Hematology, Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Urology, Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityDepartment of Nephrology, Molecular Cell Laboratory for Kidney Disease, Renji Hospital, School of Medicine, Shanghai Center for Peritoneal Dialysis Research, Shanghai Jiaotong UniversityAbstract Background Significant attention has been directed toward the high incidence of malignant tumours that occur post-transplantation. However, there are few reports of myeloid sarcomas (MSs) following renal transplantation. Case presentation This case report describes a 26-year-old male patient who presented with repeatedly high creatinine levels and hydronephrosis six months post-renal transplantation. Surgical pathology revealed ureteral MS; however, the tumour recurred following resection. Bone marrow biopsy indicated that the patient also had acute promyelocytic leukaemia. The tumour was treated with local radiotherapy, and the leukaemia was treated with systemic chemotherapy. The patient’s conditions were satisfactory at the one-year follow-up. Conclusions This report is the first to describe a ureteral MS post-renal transplantation. Our findings suggest that surgical resection combined with radiotherapy and chemotherapy can help control the status of patients with this condition.http://link.springer.com/article/10.1186/s12882-018-0838-0Myeloid sarcomaRenal transplantationAcute myeloid leukaemia
spellingShingle Liang Ying
Lei Tian
Yuanyuan Xie
Qin Wang
Xiajing Che
Jiayi Yan
Lijing Shen
Honghui Huang
Fangyuan Chen
Ming Zhang
Zhaohui Ni
Shan Mou
A case of ureteral myeloid sarcoma post-renal transplantation
BMC Nephrology
Myeloid sarcoma
Renal transplantation
Acute myeloid leukaemia
title A case of ureteral myeloid sarcoma post-renal transplantation
title_full A case of ureteral myeloid sarcoma post-renal transplantation
title_fullStr A case of ureteral myeloid sarcoma post-renal transplantation
title_full_unstemmed A case of ureteral myeloid sarcoma post-renal transplantation
title_short A case of ureteral myeloid sarcoma post-renal transplantation
title_sort case of ureteral myeloid sarcoma post renal transplantation
topic Myeloid sarcoma
Renal transplantation
Acute myeloid leukaemia
url http://link.springer.com/article/10.1186/s12882-018-0838-0
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