LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

Ciguatera poisoning is linked to the ingestion of seafood that is contaminated with ciguatoxins (CTXs). The structural variability of these polyether toxins in nature remains poorly understood due to the low concentrations present even in highly toxic fish, which makes isolation and chemical charact...

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Bibliographic Details
Main Authors: Fedor Kryuchkov, Alison Robertson, Christopher O. Miles, Elizabeth M. Mudge, Silvio Uhlig
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Marine Drugs
Subjects:
ciguatera
ciguatoxin
HRMS
<i>Gambierdiscus</i>
polyether toxin
LC–MS
Online Access:https://www.mdpi.com/1660-3397/18/4/182

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