Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases
Helicobacter pylori is the most common human infection. H. pylori is known to cause chronic gastritis and gastric and duodenal ulcers. However, the H. pylori-host interaction is not confined to the gastric mucosa, the mechanism responsible for the adaptation of this bacterium to the living condition...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
IMA-PRESS LLC
2017-04-01
|
Series: | Современная ревматология |
Subjects: | |
Online Access: | https://mrj.ima-press.net/mrj/article/view/757 |
_version_ | 1797876753690001408 |
---|---|
author | A. O. Plakhova E. S. Nikitina V. N. Sorotskaya A. E. Karateev |
author_facet | A. O. Plakhova E. S. Nikitina V. N. Sorotskaya A. E. Karateev |
author_sort | A. O. Plakhova |
collection | DOAJ |
description | Helicobacter pylori is the most common human infection. H. pylori is known to cause chronic gastritis and gastric and duodenal ulcers. However, the H. pylori-host interaction is not confined to the gastric mucosa, the mechanism responsible for the adaptation of this bacterium to the living conditions in the human body, can cause systemic immune imbalance, provoking various autoimmune reactions. The paper considers the investigations demonstrating the possible role of H. pylori as a trigger or aggravating factor in rheumatic diseases, such as rheumatoid arthritis (RA), Sjögren's syndrome and disease, systemic lupus erythematosus, and progressive systemic sclerosis. The relationship between H. pylori and autoimmune diseases is confirmed by the higher frequency of more aggressive strains of this microorganism in rheumatic diseases. There are also clinical trials showing the positive impact of H. pylori eradication on RA activity. |
first_indexed | 2024-04-10T02:07:35Z |
format | Article |
id | doaj.art-80b343c67e354c418065dd3ad3d25a10 |
institution | Directory Open Access Journal |
issn | 1996-7012 2310-158X |
language | Russian |
last_indexed | 2024-04-10T02:07:35Z |
publishDate | 2017-04-01 |
publisher | IMA-PRESS LLC |
record_format | Article |
series | Современная ревматология |
spelling | doaj.art-80b343c67e354c418065dd3ad3d25a102023-03-13T08:39:25ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2017-04-01112606710.14412/1996-7012-2017-2-60-672036Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseasesA. O. Plakhova0E. S. Nikitina1V. N. Sorotskaya2A. E. Karateev3ФГБОУ ВО «Тульский государственный университет», ТулаФГБОУ ВО «Тульский государственный университет», ТулаФГБОУ ВО «Тульский государственный университет», ТулаФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», МоскваHelicobacter pylori is the most common human infection. H. pylori is known to cause chronic gastritis and gastric and duodenal ulcers. However, the H. pylori-host interaction is not confined to the gastric mucosa, the mechanism responsible for the adaptation of this bacterium to the living conditions in the human body, can cause systemic immune imbalance, provoking various autoimmune reactions. The paper considers the investigations demonstrating the possible role of H. pylori as a trigger or aggravating factor in rheumatic diseases, such as rheumatoid arthritis (RA), Sjögren's syndrome and disease, systemic lupus erythematosus, and progressive systemic sclerosis. The relationship between H. pylori and autoimmune diseases is confirmed by the higher frequency of more aggressive strains of this microorganism in rheumatic diseases. There are also clinical trials showing the positive impact of H. pylori eradication on RA activity.https://mrj.ima-press.net/mrj/article/view/757helicobacter pyloriаутоиммунные заболеваниясиндром шёгренаболезнь шёгренасистемная красная волчанкапрогрессирующий системный склерозревматоидный артритсиндром рейноактивность заболеванияэрадикация |
spellingShingle | A. O. Plakhova E. S. Nikitina V. N. Sorotskaya A. E. Karateev Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases Современная ревматология helicobacter pylori аутоиммунные заболевания синдром шёгрена болезнь шёгрена системная красная волчанка прогрессирующий системный склероз ревматоидный артрит синдром рейно активность заболевания эрадикация |
title | Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
title_full | Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
title_fullStr | Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
title_full_unstemmed | Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
title_short | Helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
title_sort | helicobacter pylori as a trigger and aggravating factor in rheumatoid arthritis and other rheumatic diseases |
topic | helicobacter pylori аутоиммунные заболевания синдром шёгрена болезнь шёгрена системная красная волчанка прогрессирующий системный склероз ревматоидный артрит синдром рейно активность заболевания эрадикация |
url | https://mrj.ima-press.net/mrj/article/view/757 |
work_keys_str_mv | AT aoplakhova helicobacterpyloriasatriggerandaggravatingfactorinrheumatoidarthritisandotherrheumaticdiseases AT esnikitina helicobacterpyloriasatriggerandaggravatingfactorinrheumatoidarthritisandotherrheumaticdiseases AT vnsorotskaya helicobacterpyloriasatriggerandaggravatingfactorinrheumatoidarthritisandotherrheumaticdiseases AT aekarateev helicobacterpyloriasatriggerandaggravatingfactorinrheumatoidarthritisandotherrheumaticdiseases |