STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY

During childhood, 3 levels of stress were proposed: positive, tolerable and toxic. The toxic stress produced by the strong, frequent and prolonged activation of the body’s response systems is a generator of behavioral and somatic sequelae. Child abuse is present in all social media in different coun...

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Main Author: Sorin Buzinschi
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2021-06-01
Series:Romanian Journal of Pediatrics
Subjects:
Online Access:https://rjp.com.ro/articles/2021.2/RJP_2021_2_Art-01.pdf
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author Sorin Buzinschi
author_facet Sorin Buzinschi
author_sort Sorin Buzinschi
collection DOAJ
description During childhood, 3 levels of stress were proposed: positive, tolerable and toxic. The toxic stress produced by the strong, frequent and prolonged activation of the body’s response systems is a generator of behavioral and somatic sequelae. Child abuse is present in all social media in different countries. The absence of basic care has devastating effects on social and cognitive development, as found in institutionalized children. Attachment behavior and fear memory are considered stress-related biological systems. The response to stress is driven by the dynamics of cortisol secretion and its interaction with its cellular receptor. It plays a central role in the response to aggression through the process of methylation, decreased gene expression in the hippocampus and increased response to stress. Stress treatment is variable in efficiency and involves preventive measures (family and community), at school, bullying, psychological counseling, trauma-focused psychotherapy, cognitive therapy, through music.
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spelling doaj.art-80b59ba90a954eeda6d3b34d92747c522022-12-21T21:28:20ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752021-06-01702939810.37897/RJP.2021.2.1STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGYSorin Buzinschi0Faculty of Medicine, Transilvania University, Brasov, RomaniaDuring childhood, 3 levels of stress were proposed: positive, tolerable and toxic. The toxic stress produced by the strong, frequent and prolonged activation of the body’s response systems is a generator of behavioral and somatic sequelae. Child abuse is present in all social media in different countries. The absence of basic care has devastating effects on social and cognitive development, as found in institutionalized children. Attachment behavior and fear memory are considered stress-related biological systems. The response to stress is driven by the dynamics of cortisol secretion and its interaction with its cellular receptor. It plays a central role in the response to aggression through the process of methylation, decreased gene expression in the hippocampus and increased response to stress. Stress treatment is variable in efficiency and involves preventive measures (family and community), at school, bullying, psychological counseling, trauma-focused psychotherapy, cognitive therapy, through music.https://rjp.com.ro/articles/2021.2/RJP_2021_2_Art-01.pdfstresstoxic stresscortisolmethylationtreatment
spellingShingle Sorin Buzinschi
STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
Romanian Journal of Pediatrics
stress
toxic stress
cortisol
methylation
treatment
title STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
title_full STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
title_fullStr STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
title_full_unstemmed STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
title_short STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY
title_sort stress in children pathology from psychosomatics to molecular biology
topic stress
toxic stress
cortisol
methylation
treatment
url https://rjp.com.ro/articles/2021.2/RJP_2021_2_Art-01.pdf
work_keys_str_mv AT sorinbuzinschi stressinchildrenpathologyfrompsychosomaticstomolecularbiology