Pharmacokinetic interaction study between ligustrazine and valsartan in rats and its potential mechanism

Pharmacokinetic interaction study between ligustrazine and valsartan in rats and its potential mechanism

Context Ligustrazine and valsartan are commonly used drugs in the treatment of cardiac and cardiovascular disease. Objective The interaction between ligustrazine and valsartan was studied to investigate the effect of ligustrazine on the pharmacokinetics of valsartan. Materials and methods The pharma...

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Bibliographic Details
Main Authors: Yang Liu, Jiaqi Zhang, Di Wu, Liran Cui
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
metabolic stability
cyp3a4
metabolism
drug–drug interaction
Online Access:http://dx.doi.org/10.1080/13880209.2020.1859554

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