INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION
The study of mean blood velocity changes in rat mesenteric venules (15–30 µm) due to photoactivation (λ = 532 nm, 0,175 W/cm2, 300 s) of i.v. injected Rose Bengal (17 mg/kg) is represented in the article. Using in vivo biomicroscopy the progressive decrease of mean blood velocity both during the las...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2017-12-01
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| Series: | Biomedical Photonics |
| Subjects: | |
| Online Access: | https://www.pdt-journal.com/jour/article/view/181 |
| _version_ | 1797883716505174016 |
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| author | T. G. Gryshachova I. A. Mikhailova A. V. Struy S. G. Chephu N. N. Petrishchev |
| author_facet | T. G. Gryshachova I. A. Mikhailova A. V. Struy S. G. Chephu N. N. Petrishchev |
| author_sort | T. G. Gryshachova |
| collection | DOAJ |
| description | The study of mean blood velocity changes in rat mesenteric venules (15–30 µm) due to photoactivation (λ = 532 nm, 0,175 W/cm2, 300 s) of i.v. injected Rose Bengal (17 mg/kg) is represented in the article. Using in vivo biomicroscopy the progressive decrease of mean blood velocity both during the laser irradiation and after it was registered. The calculation of thermal effects in the irradiated part of microvessel due to laser absorption by hemoglobin and Rose Bengal showed the rise of temperature was not exceed 0.2оC as compared to initial level. Thus, thermal effect has nearly no significant influence on microvascular disturbances caused by Rose Bengal photoactivation. |
| first_indexed | 2024-04-10T03:55:03Z |
| format | Article |
| id | doaj.art-80b75d406c094c819c997d3a07b67c83 |
| institution | Directory Open Access Journal |
| issn | 2413-9432 |
| language | Russian |
| last_indexed | 2024-04-10T03:55:03Z |
| publishDate | 2017-12-01 |
| publisher | Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" |
| record_format | Article |
| series | Biomedical Photonics |
| spelling | doaj.art-80b75d406c094c819c997d3a07b67c832023-03-13T07:12:30ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322017-12-0163111510.24931/2413-9432-2017-6-3-11-15117INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATIONT. G. Gryshachova0I. A. Mikhailova1A. V. Struy2S. G. Chephu3N. N. Petrishchev4Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова; Национальный медицинский исследовательский центр им. В.А. Алмазова.Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова.Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова.Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова; Национальный медицинский исследовательский центр им. В.А. Алмазова.Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова; Национальный медицинский исследовательский центр им. В.А. Алмазова.The study of mean blood velocity changes in rat mesenteric venules (15–30 µm) due to photoactivation (λ = 532 nm, 0,175 W/cm2, 300 s) of i.v. injected Rose Bengal (17 mg/kg) is represented in the article. Using in vivo biomicroscopy the progressive decrease of mean blood velocity both during the laser irradiation and after it was registered. The calculation of thermal effects in the irradiated part of microvessel due to laser absorption by hemoglobin and Rose Bengal showed the rise of temperature was not exceed 0.2оC as compared to initial level. Thus, thermal effect has nearly no significant influence on microvascular disturbances caused by Rose Bengal photoactivation.https://www.pdt-journal.com/jour/article/view/181микроциркуляцияфотосенсибилизаторбенгальский розовыйсредняя скорость кровотока |
| spellingShingle | T. G. Gryshachova I. A. Mikhailova A. V. Struy S. G. Chephu N. N. Petrishchev INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION Biomedical Photonics микроциркуляция фотосенсибилизатор бенгальский розовый средняя скорость кровотока |
| title | INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION |
| title_full | INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION |
| title_fullStr | INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION |
| title_full_unstemmed | INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION |
| title_short | INFLUENCE OF PHOTOACTIVATED ROSE BENGAL ON MICROCIRCULATION |
| title_sort | influence of photoactivated rose bengal on microcirculation |
| topic | микроциркуляция фотосенсибилизатор бенгальский розовый средняя скорость кровотока |
| url | https://www.pdt-journal.com/jour/article/view/181 |
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