Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma
BackgroundNo standardized criteria for surgical resection of parasagittal sinus meningiomas (PSM) have been established, and different surgical strategies have been proposed. The aim of the present study was to investigate the efficacy and safety of a “radical” surgical strategy in the treatment of...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1364917/full |
| _version_ | 1797217447169753088 |
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| author | Zihao Duan Changlong Zhou Xiaoxiao Yan Wei Du Xiaohui Xia Hui Shi Hai Su Yi Zhang Xuenong He Qijiang Xiong |
| author_facet | Zihao Duan Changlong Zhou Xiaoxiao Yan Wei Du Xiaohui Xia Hui Shi Hai Su Yi Zhang Xuenong He Qijiang Xiong |
| author_sort | Zihao Duan |
| collection | DOAJ |
| description | BackgroundNo standardized criteria for surgical resection of parasagittal sinus meningiomas (PSM) have been established, and different surgical strategies have been proposed. The aim of the present study was to investigate the efficacy and safety of a “radical” surgical strategy in the treatment of PSM.MethodsThe clinical histories, radiological findings, pathologic features, and surgical records of 53 patients with PSM admitted by the same surgical team using the “radical” surgical strategy were retrospectively analyzed between 2018 and 2023.ResultsAmong the 53 PSM cases, 16 (30.2%) had a patent sinus proper, 28 (52.8%) had partial obstruction of the sinus proper, and 9 (17.0%) had complete obstruction of the sinus proper before the operation. During operation, Simpson grade I resection was performed in 34 (64.2%) cases and Simpson grade II in 19 (35.8%) cases. Postoperative pathologic examination suggested tumors of WHO grade I in 47 (88.7%) cases, WHO grade II in 4 (7.5%) cases, and WHO grade III in 2 (3.8%) cases. Postoperative complications primarily included a small amount of delayed intracerebral hemorrhage in 3 (5.7%) cases, exacerbation of cerebral edema in 3 (5.7%) cases, exacerbation of motor and sensory deficits in 4 (7.5%) cases, and intracranial infection in 2 (3.8%) cases. There were no cases of death or new-onset neurological dysfunction. Dizziness and headache symptoms improved to varying degrees, and a seizure-free status was achieved postoperatively. Excluding one case lost to follow-up, the average follow-up period was 33 months, and there were no cases of recurrence.ConclusionA “radical” strategy for the surgical management of PSM is effective, safe, and simple to perform, provided that the sagittal sinus is properly managed and its associated veins are protected. |
| first_indexed | 2024-04-24T12:02:00Z |
| format | Article |
| id | doaj.art-80b7920b3daf44729b4e660018759137 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-24T12:02:00Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-80b7920b3daf44729b4e6600187591372024-04-08T14:59:30ZengFrontiers Media S.A.Frontiers in Neurology1664-22952024-04-011510.3389/fneur.2024.13649171364917Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningiomaZihao DuanChanglong ZhouXiaoxiao YanWei DuXiaohui XiaHui ShiHai SuYi ZhangXuenong HeQijiang XiongBackgroundNo standardized criteria for surgical resection of parasagittal sinus meningiomas (PSM) have been established, and different surgical strategies have been proposed. The aim of the present study was to investigate the efficacy and safety of a “radical” surgical strategy in the treatment of PSM.MethodsThe clinical histories, radiological findings, pathologic features, and surgical records of 53 patients with PSM admitted by the same surgical team using the “radical” surgical strategy were retrospectively analyzed between 2018 and 2023.ResultsAmong the 53 PSM cases, 16 (30.2%) had a patent sinus proper, 28 (52.8%) had partial obstruction of the sinus proper, and 9 (17.0%) had complete obstruction of the sinus proper before the operation. During operation, Simpson grade I resection was performed in 34 (64.2%) cases and Simpson grade II in 19 (35.8%) cases. Postoperative pathologic examination suggested tumors of WHO grade I in 47 (88.7%) cases, WHO grade II in 4 (7.5%) cases, and WHO grade III in 2 (3.8%) cases. Postoperative complications primarily included a small amount of delayed intracerebral hemorrhage in 3 (5.7%) cases, exacerbation of cerebral edema in 3 (5.7%) cases, exacerbation of motor and sensory deficits in 4 (7.5%) cases, and intracranial infection in 2 (3.8%) cases. There were no cases of death or new-onset neurological dysfunction. Dizziness and headache symptoms improved to varying degrees, and a seizure-free status was achieved postoperatively. Excluding one case lost to follow-up, the average follow-up period was 33 months, and there were no cases of recurrence.ConclusionA “radical” strategy for the surgical management of PSM is effective, safe, and simple to perform, provided that the sagittal sinus is properly managed and its associated veins are protected.https://www.frontiersin.org/articles/10.3389/fneur.2024.1364917/fullsagittal sinusmeningiomasurgical strategymicrosurgeryparasagittal sinus meningioma |
| spellingShingle | Zihao Duan Changlong Zhou Xiaoxiao Yan Wei Du Xiaohui Xia Hui Shi Hai Su Yi Zhang Xuenong He Qijiang Xiong Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma Frontiers in Neurology sagittal sinus meningioma surgical strategy microsurgery parasagittal sinus meningioma |
| title | Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma |
| title_full | Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma |
| title_fullStr | Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma |
| title_full_unstemmed | Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma |
| title_short | Efficacy and safety of a “radical” surgical strategy in the treatment of parasagittal sinus meningioma |
| title_sort | efficacy and safety of a radical surgical strategy in the treatment of parasagittal sinus meningioma |
| topic | sagittal sinus meningioma surgical strategy microsurgery parasagittal sinus meningioma |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1364917/full |
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