Insights into COVID-19 vaccines development: Translation from benchside to bedside

Over the past decades, the rapid pace of vaccine development saved 37 million lives, mostly children. The ongoing corona virus disease (COVID-19) pandemic caused the death of more than 4 million worldwide. During 2020, to encounter the pandemic, scientists developed more than 300 vaccines projects a...

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Main Authors: Marwa Houssein, Aya El Asir Al Hossainy, Jana Al soussi, Jana El Batch, Lana El-Samadi, Sherine El Imam, Rawan Fakih, Hoda Dakdouk, Mahmoud Khalil
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Health Sciences Review
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772632022000290
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author Marwa Houssein
Aya El Asir Al Hossainy
Jana Al soussi
Jana El Batch
Lana El-Samadi
Sherine El Imam
Rawan Fakih
Hoda Dakdouk
Mahmoud Khalil
author_facet Marwa Houssein
Aya El Asir Al Hossainy
Jana Al soussi
Jana El Batch
Lana El-Samadi
Sherine El Imam
Rawan Fakih
Hoda Dakdouk
Mahmoud Khalil
author_sort Marwa Houssein
collection DOAJ
description Over the past decades, the rapid pace of vaccine development saved 37 million lives, mostly children. The ongoing corona virus disease (COVID-19) pandemic caused the death of more than 4 million worldwide. During 2020, to encounter the pandemic, scientists developed more than 300 vaccines projects against SARS-CoV (severe acute respiratory syndrome coronavirus 2). In 2021, the results emerging from the clinical trials led to the approval and rollout of few vaccines in different countries. To date, at least one dose of a COVID-19 vaccine has been received by more than 3.81 billion people worldwide, equal to about 49.7 percent of the world population. This review was written to the aim of providing a snapshot of COVID-19 disease, highlighting the well-known vaccines, and, finally understanding the effect of mix and match vaccines from different types.
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spelling doaj.art-80bb1c79ada74125a449883346f38b622022-12-22T04:26:14ZengElsevierHealth Sciences Review2772-63202022-09-014100040Insights into COVID-19 vaccines development: Translation from benchside to bedsideMarwa Houssein0Aya El Asir Al Hossainy1Jana Al soussi2Jana El Batch3Lana El-Samadi4Sherine El Imam5Rawan Fakih6Hoda Dakdouk7Mahmoud Khalil8Department of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, Lebanon; Department of General Sciences and English Language, College of Applied Sciences, Al Maarefa University, Riyadh, Saudi ArabiaDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, LebanonDepartment of Biological Sciences, Faculty of Science, Beirut Arab University, Beirut, Lebanon; Molecular Biology Unit, Zoology Department, Faculty of Science, Alexandria University, Alexandria, Egypt; Corresponding author. Molecular Biology Unit, Zoology Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Phone: (+2) 01223256303. Orcid: https://orcid.org/0000-0001-7629-4357.Over the past decades, the rapid pace of vaccine development saved 37 million lives, mostly children. The ongoing corona virus disease (COVID-19) pandemic caused the death of more than 4 million worldwide. During 2020, to encounter the pandemic, scientists developed more than 300 vaccines projects against SARS-CoV (severe acute respiratory syndrome coronavirus 2). In 2021, the results emerging from the clinical trials led to the approval and rollout of few vaccines in different countries. To date, at least one dose of a COVID-19 vaccine has been received by more than 3.81 billion people worldwide, equal to about 49.7 percent of the world population. This review was written to the aim of providing a snapshot of COVID-19 disease, highlighting the well-known vaccines, and, finally understanding the effect of mix and match vaccines from different types.http://www.sciencedirect.com/science/article/pii/S2772632022000290Human coronaviruses familySARS-CoV-2 variantsSinopharmAstrazenecaSputnik vJohnson & Johnson
spellingShingle Marwa Houssein
Aya El Asir Al Hossainy
Jana Al soussi
Jana El Batch
Lana El-Samadi
Sherine El Imam
Rawan Fakih
Hoda Dakdouk
Mahmoud Khalil
Insights into COVID-19 vaccines development: Translation from benchside to bedside
Health Sciences Review
Human coronaviruses family
SARS-CoV-2 variants
Sinopharm
Astrazeneca
Sputnik v
Johnson & Johnson
title Insights into COVID-19 vaccines development: Translation from benchside to bedside
title_full Insights into COVID-19 vaccines development: Translation from benchside to bedside
title_fullStr Insights into COVID-19 vaccines development: Translation from benchside to bedside
title_full_unstemmed Insights into COVID-19 vaccines development: Translation from benchside to bedside
title_short Insights into COVID-19 vaccines development: Translation from benchside to bedside
title_sort insights into covid 19 vaccines development translation from benchside to bedside
topic Human coronaviruses family
SARS-CoV-2 variants
Sinopharm
Astrazeneca
Sputnik v
Johnson & Johnson
url http://www.sciencedirect.com/science/article/pii/S2772632022000290
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