Transcriptomic changes in porcine articular cartilage one year following disruption of the anterior cruciate ligament.

Transcriptomic changes in porcine articular cartilage one year following disruption of the anterior cruciate ligament.

To determine the transcriptomic changes seen in early- to mid-stage posttraumatic osteoarthritis (PTOA) development, 72 Yucatan minipigs underwent transection of the anterior cruciate ligament. Subjects were randomized to no further intervention, ligament reconstruction, or ligament repair, followed...

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Bibliographic Details
Main Authors: Jonah I Donnenfield, Naga Padmini Karamchedu, Benedikt L Proffen, Janine Molino, Braden C Fleming, Martha M Murray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284777

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