HIF-1α and GLUT-1 Expression in Atypical Endometrial Hyperplasia, Type I and II Endometrial Carcinoma: A Potential Role in Pathogenesis

HIF-1α and GLUT-1 Expression in Atypical Endometrial Hyperplasia, Type I and II Endometrial Carcinoma: A Potential Role in Pathogenesis

Introduction: Hypoxia-Inducible Factor 1a (HIF-1α) is one of the major adaptive responses to hypoxia, regulating the activity of glucose transporter -1 (GLUT-1), responsible for glucose uptake. Aim: To evaluate the immunohistochemical expression of both HIF-1α and GLUT-1 in type I and II endomet...

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Bibliographic Details
Main Authors: Dalia Rifaat Al-Sharaky, Asmaa Gaber Abdou, Moshira Mohammed Abdel Wahed, Hend Abdou Kassem
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-05-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
hypoxic markers
immunohistochemistry
necrosis
Online Access:https://jcdr.net/articles/PDF/7805/19576_CE(RA1)_F(T)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdf

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