Mesenchymal Stem Cell Treatment Prevents Post-Stroke Dysregulation of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases

Mesenchymal Stem Cell Treatment Prevents Post-Stroke Dysregulation of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases

Background/Aims: Stem cell treatment is one of the potential treatment options for ischemic stroke. We recently demonstrated a protective effect of human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs) in a rat model of ischemic stroke. The treatment attenuated apoptosis and prevente...

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Bibliographic Details
Main Authors: Bharath Chelluboina, Koteswara Rao Nalamolu, Gustavo G. Mendez, Jeffrey D. Klopfenstein, David M Pinson, David Z Wang, Krishna Kumar Veeravalli
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Stem cells
Ischemia
Reperfusion
MMPs
TIMPs
Induction
Online Access:https://www.karger.com/Article/FullText/485533

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