13C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis

13C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis

Poly-γ-glutamic acid (γ-PGA) is an anionic polymer with various applications. Teichoic acid (TA) is a special component of cell wall in gram-positive bacteria, and its D-alanylation modification can change the net negative charge of cell surface, autolysin activity and cationic binding efficiency, a...

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Bibliographic Details
Main Authors: Penghui He, Ni Wan, Dongbo Cai, Shiying Hu, Yaozhong Chen, Shunyi Li, Shouwen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
Bacillus licheniformis
poly-γ-glutamic acid
13C-metabolic flux analysis
dltB
cell surface negative charge
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00105/full

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