Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic

Amiodarone is a common antiarrhythmic drug that is utilised in clinical practice and is associated with pulmonary toxicity. The most common form of pulmonary complication is interstitial pneumonitis which is treated with discontinuation of amiodarone and initiation of corticosteroids. Amiodarone-...

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Main Authors: Meor Azraai, Marcus McMahon, Ronald Dick
Format: Article
Language:English
Published: IMR Press 2021-03-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://rcm.imrpress.com/fileup/2153-8174/PDF/1617068689998-482696708.pdf
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author Meor Azraai
Marcus McMahon
Ronald Dick
author_facet Meor Azraai
Marcus McMahon
Ronald Dick
author_sort Meor Azraai
collection DOAJ
description Amiodarone is a common antiarrhythmic drug that is utilised in clinical practice and is associated with pulmonary toxicity. The most common form of pulmonary complication is interstitial pneumonitis which is treated with discontinuation of amiodarone and initiation of corticosteroids. Amiodarone-induced pulmonary eosinophilia is a rare complication of amiodarone therapy, with blood and pulmonary eosinophilia the predominant features. During the COVID-19 era, the incidence of delay in treatment of pulmonary pathology is also delayed due to the effort of excluding COVID-19 infection. Here we report a case of a 64-year-old man who developed eosinophilic pneumonia after initiation of amiodarone therapy, and the investigations required to exclude other forms of pulmonary toxicity. We also reviewed the effect of COVID-19 testing in the management of patients presenting with respiratory distress.
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spelling doaj.art-80c750096f244723a22f49a1003cc1df2022-12-22T01:34:26ZengIMR PressReviews in Cardiovascular Medicine2153-81742021-03-0122118118410.31083/j.rcm.2021.01.2671617068689998-482696708Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemicMeor Azraai0Marcus McMahon1Ronald Dick2Department of Cardiology, Epworth Healthcare, Melbourne, 3121 Victoria, AustraliaDepartment of Respiratory Medicine, Epworth Healthcare, Melbourne, 3121 Victoria, AustraliaDepartment of Cardiology, Epworth Healthcare, Melbourne, 3121 Victoria, AustraliaAmiodarone is a common antiarrhythmic drug that is utilised in clinical practice and is associated with pulmonary toxicity. The most common form of pulmonary complication is interstitial pneumonitis which is treated with discontinuation of amiodarone and initiation of corticosteroids. Amiodarone-induced pulmonary eosinophilia is a rare complication of amiodarone therapy, with blood and pulmonary eosinophilia the predominant features. During the COVID-19 era, the incidence of delay in treatment of pulmonary pathology is also delayed due to the effort of excluding COVID-19 infection. Here we report a case of a 64-year-old man who developed eosinophilic pneumonia after initiation of amiodarone therapy, and the investigations required to exclude other forms of pulmonary toxicity. We also reviewed the effect of COVID-19 testing in the management of patients presenting with respiratory distress.https://rcm.imrpress.com/fileup/2153-8174/PDF/1617068689998-482696708.pdfamiodaronepulmonary eosinophiliacovid-19amiodarone-induced pulmonary toxicitycorticosteroids
spellingShingle Meor Azraai
Marcus McMahon
Ronald Dick
Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
Reviews in Cardiovascular Medicine
amiodarone
pulmonary eosinophilia
covid-19
amiodarone-induced pulmonary toxicity
corticosteroids
title Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
title_full Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
title_fullStr Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
title_full_unstemmed Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
title_short Case report of amiodarone-associated allergic pneumonitis amidst the COVID-19 pandemic
title_sort case report of amiodarone associated allergic pneumonitis amidst the covid 19 pandemic
topic amiodarone
pulmonary eosinophilia
covid-19
amiodarone-induced pulmonary toxicity
corticosteroids
url https://rcm.imrpress.com/fileup/2153-8174/PDF/1617068689998-482696708.pdf
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