Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen
In this work, Ni-Co layered double hydroxide (Ni–Co LDH) hollow nanostructures were synthesized and characterized by X-ray diffraction (XRD), field emission-scanning electron microscopy (FE-SEM), and Fourier-transform infrared spectroscopy (FT-IR) techniques. A screen-printed electrode (SPE) surface...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/12/10/872 |
| _version_ | 1797474788010098688 |
|---|---|
| author | Hadi Beitollahi Zahra Dourandish Somayeh Tajik Fatemeh Sharifi Peyman Mohammadzadeh Jahani |
| author_facet | Hadi Beitollahi Zahra Dourandish Somayeh Tajik Fatemeh Sharifi Peyman Mohammadzadeh Jahani |
| author_sort | Hadi Beitollahi |
| collection | DOAJ |
| description | In this work, Ni-Co layered double hydroxide (Ni–Co LDH) hollow nanostructures were synthesized and characterized by X-ray diffraction (XRD), field emission-scanning electron microscopy (FE-SEM), and Fourier-transform infrared spectroscopy (FT-IR) techniques. A screen-printed electrode (SPE) surface was modified with as-fabricated Ni–Co LDHs to achieve a new sensing platform for determination of sumatriptan. The electrochemical behavior of the Ni–Co LDH-modified SPE (Ni-CO LDH/SPE) for sumatriptan determination was investigated using voltammetric methods. Compared with bare SPE, the presence of Ni-Co LDH was effective in the enhancement of electron transport rate between the electrode and analyte, as well as in the significant reduction of the overpotential of sumatriptan oxidation. Differential pulse voltammetry (DPV) was applied to perform a quantitative analysis of sumatriptan. The linearity range was found to be between 0.01 and 435.0 μM. The limits of detection (LOD) and sensitivity were 0.002 ± 0.0001 μM and 0.1017 ± 0.0001 μA/μM, respectively. In addition, the performance of the Ni-CO LDH/SPE for the determination of sumatriptan in the presence of naproxen was studied. Simultaneous analysis of sumatriptan with naproxen showed well-separated peaks leading to a quick and selective analysis of sumatriptan. Furthermore, the practical applicability of the prepared Ni-CO LDH/SPE sensor was examined in pharmaceutical and biological samples with satisfactory recovery results. |
| first_indexed | 2024-03-09T20:36:03Z |
| format | Article |
| id | doaj.art-80c8209f6b99459cbc1f6f9bc63868e9 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T20:36:03Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-80c8209f6b99459cbc1f6f9bc63868e92023-11-23T23:12:01ZengMDPI AGBiosensors2079-63742022-10-01121087210.3390/bios12100872Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and NaproxenHadi Beitollahi0Zahra Dourandish1Somayeh Tajik2Fatemeh Sharifi3Peyman Mohammadzadeh Jahani4Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman 7631885356, IranDepartment of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman 76175-133, IranResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman 7616913555, IranResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman 7616913555, IranSchool of Medicine, Bam University of Medical Sciences, Bam 7661771967, IranIn this work, Ni-Co layered double hydroxide (Ni–Co LDH) hollow nanostructures were synthesized and characterized by X-ray diffraction (XRD), field emission-scanning electron microscopy (FE-SEM), and Fourier-transform infrared spectroscopy (FT-IR) techniques. A screen-printed electrode (SPE) surface was modified with as-fabricated Ni–Co LDHs to achieve a new sensing platform for determination of sumatriptan. The electrochemical behavior of the Ni–Co LDH-modified SPE (Ni-CO LDH/SPE) for sumatriptan determination was investigated using voltammetric methods. Compared with bare SPE, the presence of Ni-Co LDH was effective in the enhancement of electron transport rate between the electrode and analyte, as well as in the significant reduction of the overpotential of sumatriptan oxidation. Differential pulse voltammetry (DPV) was applied to perform a quantitative analysis of sumatriptan. The linearity range was found to be between 0.01 and 435.0 μM. The limits of detection (LOD) and sensitivity were 0.002 ± 0.0001 μM and 0.1017 ± 0.0001 μA/μM, respectively. In addition, the performance of the Ni-CO LDH/SPE for the determination of sumatriptan in the presence of naproxen was studied. Simultaneous analysis of sumatriptan with naproxen showed well-separated peaks leading to a quick and selective analysis of sumatriptan. Furthermore, the practical applicability of the prepared Ni-CO LDH/SPE sensor was examined in pharmaceutical and biological samples with satisfactory recovery results.https://www.mdpi.com/2079-6374/12/10/872Ni-Co layered double hydroxide hollow nanostructuresscreen-printed electrodesumatriptannaproxen |
| spellingShingle | Hadi Beitollahi Zahra Dourandish Somayeh Tajik Fatemeh Sharifi Peyman Mohammadzadeh Jahani Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen Biosensors Ni-Co layered double hydroxide hollow nanostructures screen-printed electrode sumatriptan naproxen |
| title | Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen |
| title_full | Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen |
| title_fullStr | Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen |
| title_full_unstemmed | Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen |
| title_short | Electrochemical Sensor Based on Ni-Co Layered Double Hydroxide Hollow Nanostructures for Ultrasensitive Detection of Sumatriptan and Naproxen |
| title_sort | electrochemical sensor based on ni co layered double hydroxide hollow nanostructures for ultrasensitive detection of sumatriptan and naproxen |
| topic | Ni-Co layered double hydroxide hollow nanostructures screen-printed electrode sumatriptan naproxen |
| url | https://www.mdpi.com/2079-6374/12/10/872 |
| work_keys_str_mv | AT hadibeitollahi electrochemicalsensorbasedonnicolayereddoublehydroxidehollownanostructuresforultrasensitivedetectionofsumatriptanandnaproxen AT zahradourandish electrochemicalsensorbasedonnicolayereddoublehydroxidehollownanostructuresforultrasensitivedetectionofsumatriptanandnaproxen AT somayehtajik electrochemicalsensorbasedonnicolayereddoublehydroxidehollownanostructuresforultrasensitivedetectionofsumatriptanandnaproxen AT fatemehsharifi electrochemicalsensorbasedonnicolayereddoublehydroxidehollownanostructuresforultrasensitivedetectionofsumatriptanandnaproxen AT peymanmohammadzadehjahani electrochemicalsensorbasedonnicolayereddoublehydroxidehollownanostructuresforultrasensitivedetectionofsumatriptanandnaproxen |