Role of EGF inhibitors in the treatment of recurrent or metastatic squamous cell head and neck cancer

Jochen H LorchDana Farber Cancer institute, Boston, MA, USAAbstract: Squamous cell cancer of the head and neck (SCCHN) is a major contributor to morbidity and mortality worldwide. In recent years, inhibition of the epidermal growth factor receptor has become an established treatment strategy in SCCH...

Full description

Bibliographic Details
Main Author: Jochen H Lorch
Format: Article
Language:English
Published: Dove Medical Press 2009-11-01
Series:Cancer Management and Research
Online Access:http://www.dovepress.com/role-of-egf-inhibitors-in-the-treatment-of-recurrent-or-metastatic-squ-a3689
Description
Summary:Jochen H LorchDana Farber Cancer institute, Boston, MA, USAAbstract: Squamous cell cancer of the head and neck (SCCHN) is a major contributor to morbidity and mortality worldwide. In recent years, inhibition of the epidermal growth factor receptor has become an established treatment strategy in SCCHN both in the up-front treatment and in the recurrent and metastatic setting. This review summarizes the most important developments of the recent past and provides an overview of newer developments. Keywords: squamous cell cancer, head, neck, epidermal growth factor receptor
ISSN:1179-1322