2’-Fucosyllactose inhibits proliferation of Clostridioides difficile ATCC 43599 in the CDi-screen, an in vitro model simulating Clostridioides difficile infection

2’-Fucosyllactose inhibits proliferation of Clostridioides difficile ATCC 43599 in the CDi-screen, an in vitro model simulating Clostridioides difficile infection

BackgroundClostridioides difficile is a Gram-positive anaerobic bacterium that can produce the toxins TcdA and/or TcdB and is considered an opportunistic pathogen. C. difficile is mainly transmitted as endospores, which germinate to produce the pathogenic vegetative cells under suitable conditions i...

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Bibliographic Details
Main Authors: Maria Wiese, Frank H. J. Schuren, Wiep Klaas Smits, Ed J. Kuijper, Anita Ouwens, Margreet Heerikhuisen, Louise Vigsnaes, Tim J. van den Broek, Paulo de Boer, Roy C. Montijn, Jos M. B. M. van der Vossen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Clostridioides difficile infection
in vitro gut model
screening
interventions
human milk oligosaccharide
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.991150/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.991150/full

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