Different Regimes of Opto-fluidics for Biological Manipulation
<b> </b>Metallic structures can be used for the localized heating of fluid and the controlled generation of microfluidic currents. Carefully designed currents can move and trap small particles and cells. Here we demonstrate a new bi-metallic substrate that allows much more powerful micro...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-11-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-666X/10/12/802 |
| _version_ | 1811215440638115840 |
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| author | John T. Winskas Hao Wang Arsenii Zhdanov Surya Cheemalapati Andrew Deonarine Sandy Westerheide Anna Pyayt |
| author_facet | John T. Winskas Hao Wang Arsenii Zhdanov Surya Cheemalapati Andrew Deonarine Sandy Westerheide Anna Pyayt |
| author_sort | John T. Winskas |
| collection | DOAJ |
| description | <b> </b>Metallic structures can be used for the localized heating of fluid and the controlled generation of microfluidic currents. Carefully designed currents can move and trap small particles and cells. Here we demonstrate a new bi-metallic substrate that allows much more powerful micro-scale manipulation. We show that there are multiple regimes of opto-fluidic manipulation that can be controlled by an external laser power. While the lowest power does not affect even small objects, medium power can be used for efficiently capturing and trapping particles and cells. Finally, the high-power regime can be used for 3D levitation that, for the first time, has been demonstrated in this paper. Additionally, we demonstrate opto-fluidic manipulation for an extraordinarily dynamic range of masses extending eight orders of magnitude: from 80 fg nano-wires to 5.4 µg live worms. |
| first_indexed | 2024-04-12T06:22:40Z |
| format | Article |
| id | doaj.art-80c9f3c677364b9191972810962063be |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-04-12T06:22:40Z |
| publishDate | 2019-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-80c9f3c677364b9191972810962063be2022-12-22T03:44:16ZengMDPI AGMicromachines2072-666X2019-11-01101280210.3390/mi10120802mi10120802Different Regimes of Opto-fluidics for Biological ManipulationJohn T. Winskas0Hao Wang1Arsenii Zhdanov2Surya Cheemalapati3Andrew Deonarine4Sandy Westerheide5Anna Pyayt6Department of Chemical and Biomedical Engineering, University of South Florida, 4202 E. Fowler Ave, ENB118, Tampa, FL 33620, USADepartment of Chemical and Biomedical Engineering, University of South Florida, 4202 E. Fowler Ave, ENB118, Tampa, FL 33620, USADepartment of Chemical and Biomedical Engineering, University of South Florida, 4202 E. Fowler Ave, ENB118, Tampa, FL 33620, USADepartment of Chemical and Biomedical Engineering, University of South Florida, 4202 E. Fowler Ave, ENB118, Tampa, FL 33620, USADepartment of Cell Biology, Microbiology and Molecular Biology, University of South Florida, 4202 E, Fowler Ave. ENB118, Tampa, FL 33620, USADepartment of Cell Biology, Microbiology and Molecular Biology, University of South Florida, 4202 E, Fowler Ave. ENB118, Tampa, FL 33620, USADepartment of Chemical and Biomedical Engineering, University of South Florida, 4202 E. Fowler Ave, ENB118, Tampa, FL 33620, USA<b> </b>Metallic structures can be used for the localized heating of fluid and the controlled generation of microfluidic currents. Carefully designed currents can move and trap small particles and cells. Here we demonstrate a new bi-metallic substrate that allows much more powerful micro-scale manipulation. We show that there are multiple regimes of opto-fluidic manipulation that can be controlled by an external laser power. While the lowest power does not affect even small objects, medium power can be used for efficiently capturing and trapping particles and cells. Finally, the high-power regime can be used for 3D levitation that, for the first time, has been demonstrated in this paper. Additionally, we demonstrate opto-fluidic manipulation for an extraordinarily dynamic range of masses extending eight orders of magnitude: from 80 fg nano-wires to 5.4 µg live worms.https://www.mdpi.com/2072-666X/10/12/802opto-fluidicsmicro-manipulationcellsmicroparticles |
| spellingShingle | John T. Winskas Hao Wang Arsenii Zhdanov Surya Cheemalapati Andrew Deonarine Sandy Westerheide Anna Pyayt Different Regimes of Opto-fluidics for Biological Manipulation Micromachines opto-fluidics micro-manipulation cells microparticles |
| title | Different Regimes of Opto-fluidics for Biological Manipulation |
| title_full | Different Regimes of Opto-fluidics for Biological Manipulation |
| title_fullStr | Different Regimes of Opto-fluidics for Biological Manipulation |
| title_full_unstemmed | Different Regimes of Opto-fluidics for Biological Manipulation |
| title_short | Different Regimes of Opto-fluidics for Biological Manipulation |
| title_sort | different regimes of opto fluidics for biological manipulation |
| topic | opto-fluidics micro-manipulation cells microparticles |
| url | https://www.mdpi.com/2072-666X/10/12/802 |
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