Blood Differential Gene Expression in Patients with Chronic Heart Failure and Systemic Iron Deficiency: Pathways Involved in Pathophysiology and Impact on Clinical Outcomes

Blood Differential Gene Expression in Patients with Chronic Heart Failure and Systemic Iron Deficiency: Pathways Involved in Pathophysiology and Impact on Clinical Outcomes

Background: Iron deficiency is a common disorder in patients with heart failure and is related with adverse outcomes and poor quality of life. Previous experimental studies have shown biological connections between iron homeostasis, mitochondrial metabolism, and myocardial function. However, the mec...

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Main Authors: Carles Díez-López, Marta Tajes Orduña, Cristina Enjuanes Grau, Pedro Moliner Borja, José González-Costello, Elena García-Romero, Josep Francesch Manzano, Sergi Yun Viladomat, Santiago Jiménez-Marrero, Raul Ramos-Polo, Maria del Mar Ras Jiménez, Josep Comín-Colet
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Clinical Medicine
Subjects:
heart failure
iron deficiency
cardiac metabolism
mitochondria
Online Access:https://www.mdpi.com/2077-0383/10/21/4937

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