Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus
Barrett´s esophagus (BE) is established as a premalignant condition in the distal esophagus. Current surveillance guidelines recommend random biopsies every 1-2 cm at intervals of 3-5 years. Advanced endoscopic imaging of BE underwent several technical revolutions within the last decade inc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00042/full |
| _version_ | 1818615813443158016 |
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| author | Helmut eNeumann Cord eLangner Markus F. Neurath Michael eVieth |
| author_facet | Helmut eNeumann Cord eLangner Markus F. Neurath Michael eVieth |
| author_sort | Helmut eNeumann |
| collection | DOAJ |
| description | Barrett´s esophagus (BE) is established as a premalignant condition in the distal esophagus. Current surveillance guidelines recommend random biopsies every 1-2 cm at intervals of 3-5 years. Advanced endoscopic imaging of BE underwent several technical revolutions within the last decade including broad-field (red-flag) techniques (e.g. chromoendoscopy) and small-field techniques with confocal laser endomicroscopy (CLE) at the forefront. In this review we will focus on advanced endoscopic imaging using CLE for the diagnosis and characterization of BE and associated neoplasia. In addition, we will critically discuss the technique of CLE and provide some tricks and hints for the daily routine practice of CLE for diagnosis of BE. |
| first_indexed | 2024-12-16T16:39:52Z |
| format | Article |
| id | doaj.art-80cc44f4dbb444daab4addd62a0086a7 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-16T16:39:52Z |
| publishDate | 2012-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-80cc44f4dbb444daab4addd62a0086a72022-12-21T22:24:21ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2012-05-01210.3389/fonc.2012.0004222261Confocal laser endomicroscopy for diagnosis of Barrett´s esophagusHelmut eNeumann0Cord eLangner1Markus F. Neurath2Michael eVieth3University of Erlangen-NurembergMedical University GrazUniversity of Erlangen-NurembergKlinikum BayreuthBarrett´s esophagus (BE) is established as a premalignant condition in the distal esophagus. Current surveillance guidelines recommend random biopsies every 1-2 cm at intervals of 3-5 years. Advanced endoscopic imaging of BE underwent several technical revolutions within the last decade including broad-field (red-flag) techniques (e.g. chromoendoscopy) and small-field techniques with confocal laser endomicroscopy (CLE) at the forefront. In this review we will focus on advanced endoscopic imaging using CLE for the diagnosis and characterization of BE and associated neoplasia. In addition, we will critically discuss the technique of CLE and provide some tricks and hints for the daily routine practice of CLE for diagnosis of BE.http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00042/fullAdenocarcinomaFluoresceinMolecular ImagingiCLEpCLEadvanced imaging |
| spellingShingle | Helmut eNeumann Cord eLangner Markus F. Neurath Michael eVieth Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus Frontiers in Oncology Adenocarcinoma Fluorescein Molecular Imaging iCLE pCLE advanced imaging |
| title | Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus |
| title_full | Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus |
| title_fullStr | Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus |
| title_full_unstemmed | Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus |
| title_short | Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus |
| title_sort | confocal laser endomicroscopy for diagnosis of barrett 180 s esophagus |
| topic | Adenocarcinoma Fluorescein Molecular Imaging iCLE pCLE advanced imaging |
| url | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00042/full |
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