Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care
The world faces the threat of increasing antimicrobial resistance, and there is growing consensus that swift action must be taken to improve the rational use of antibiotics and increase the stewardship of antibiotics to safeguard this key resource in modern healthcare. This paper provides the perspe...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1166742/full |
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| author | Oliver Van Hecke Oliver Van Hecke Lars Bjerrum Ivan Gentile Rogier Hopstaken Hasse Melbye Andreas Plate Jan Y. Verbakel Jan Y. Verbakel Carl Llor Annamaria Staiano |
| author_facet | Oliver Van Hecke Oliver Van Hecke Lars Bjerrum Ivan Gentile Rogier Hopstaken Hasse Melbye Andreas Plate Jan Y. Verbakel Jan Y. Verbakel Carl Llor Annamaria Staiano |
| author_sort | Oliver Van Hecke |
| collection | DOAJ |
| description | The world faces the threat of increasing antimicrobial resistance, and there is growing consensus that swift action must be taken to improve the rational use of antibiotics and increase the stewardship of antibiotics to safeguard this key resource in modern healthcare. This paper provides the perspective of an international group of experts on the role of C-reactive protein point-of-care testing (CRP POCT) and other complementary strategies to improve antibiotic stewardship in primary care, with regards to the diagnosis and treatment of adult patients presenting symptoms of lower respiratory tract infections (LRTIs). It provides guidance regarding the clinical assessment of symptoms in combination with C-reactive protein (CRP) results, at the point of care, to support the management decision, and discusses enhanced patient communication and delayed prescribing as complementary strategies to decrease the inappropriate use of antibiotics. Recommendation: CRP POCT should be promoted to improve the identification of adults presenting with symptoms of LRTIs in primary care who might gain additional benefit from antibiotic treatment. Appropriateness of antibiotic use can be maximized when CRP POCT is used together with complementary strategies such as enhanced communication skills training and delayed prescribing in addition to routine safety netting. |
| first_indexed | 2024-03-13T08:42:07Z |
| format | Article |
| id | doaj.art-80cdf5a5996a4543b4f2285b6b94676d |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-13T08:42:07Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-80cdf5a5996a4543b4f2285b6b94676d2023-05-30T08:53:53ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-05-011010.3389/fmed.2023.11667421166742Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary careOliver Van Hecke0Oliver Van Hecke1Lars Bjerrum2Ivan Gentile3Rogier Hopstaken4Hasse Melbye5Andreas Plate6Jan Y. Verbakel7Jan Y. Verbakel8Carl Llor9Annamaria Staiano10Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United KingdomNuffield Department of Primary Care Health Sciences, NIHR Community Healthcare Medtech and IVD Cooperative, University of Oxford, Oxford, United KingdomDepartment of Public Health, University of Copenhagen, Copenhagen, DenmarkDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples Federico II, Naples, ItalyDepartment of General Practice, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Centre, Maastricht, NetherlandsGeneral Practice Research Unit, Department of Community Medicine, The Arctic University of Norway, Tromso, NorwayInstitute of Primary Care, University of Zurich and University Hospital Zurich, Zurich, SwitzerlandEPI-Centre, Department of Public Health and Primary Care, Academisch Centrum voor Huisartsgeneeskunde, Leuven and NIHR Community Healthcare Medtech and IVD Cooperative, Leuven, BelgiumNuffield Department of Primary Care Health Sciences, NIHR Community Healthcare Medtech and IVD Cooperative, University of Oxford, Oxford, United KingdomDepartment of Public Health and Primary Care, University of Southern Denmark, Odense, Denmark0Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyThe world faces the threat of increasing antimicrobial resistance, and there is growing consensus that swift action must be taken to improve the rational use of antibiotics and increase the stewardship of antibiotics to safeguard this key resource in modern healthcare. This paper provides the perspective of an international group of experts on the role of C-reactive protein point-of-care testing (CRP POCT) and other complementary strategies to improve antibiotic stewardship in primary care, with regards to the diagnosis and treatment of adult patients presenting symptoms of lower respiratory tract infections (LRTIs). It provides guidance regarding the clinical assessment of symptoms in combination with C-reactive protein (CRP) results, at the point of care, to support the management decision, and discusses enhanced patient communication and delayed prescribing as complementary strategies to decrease the inappropriate use of antibiotics. Recommendation: CRP POCT should be promoted to improve the identification of adults presenting with symptoms of LRTIs in primary care who might gain additional benefit from antibiotic treatment. Appropriateness of antibiotic use can be maximized when CRP POCT is used together with complementary strategies such as enhanced communication skills training and delayed prescribing in addition to routine safety netting.https://www.frontiersin.org/articles/10.3389/fmed.2023.1166742/fullCRPGPLRTIantibiotic stewardshippoint-of-care testrespiratory tract infections |
| spellingShingle | Oliver Van Hecke Oliver Van Hecke Lars Bjerrum Ivan Gentile Rogier Hopstaken Hasse Melbye Andreas Plate Jan Y. Verbakel Jan Y. Verbakel Carl Llor Annamaria Staiano Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care Frontiers in Medicine CRP GP LRTI antibiotic stewardship point-of-care test respiratory tract infections |
| title | Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| title_full | Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| title_fullStr | Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| title_full_unstemmed | Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| title_short | Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| title_sort | guidance on c reactive protein point of care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care |
| topic | CRP GP LRTI antibiotic stewardship point-of-care test respiratory tract infections |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1166742/full |
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