Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status
Dietary inflammatory potential has been proven to be correlated with the incidence of diabetes and cardiovascular diseases. However, the evidence regarding the impact of dietary inflammatory patterns on long-term mortality is scarce. This cohort study aims to investigate the dietary inflammatory pat...
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MDPI AG
2022-06-01
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| Online Access: | https://www.mdpi.com/2072-6643/14/13/2556 |
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| author | Sheng Yuan Chenxi Song Rui Zhang Jining He Kefei Dou |
| author_facet | Sheng Yuan Chenxi Song Rui Zhang Jining He Kefei Dou |
| author_sort | Sheng Yuan |
| collection | DOAJ |
| description | Dietary inflammatory potential has been proven to be correlated with the incidence of diabetes and cardiovascular diseases. However, the evidence regarding the impact of dietary inflammatory patterns on long-term mortality is scarce. This cohort study aims to investigate the dietary inflammatory pattern of the general US individuals by baseline glycemic status and to estimate its association with long-term mortality. A total of 20,762 general American adults with different glycemic statuses from the National Health and Nutrition Examination Survey were included. We extracted 24-h dietary information, and the dietary inflammatory index (DII) was calculated. The outcomes were defined as 5-year all-cause and cardiovascular mortality. Compared with the normoglycemia group, individuals with prediabetes and type 2 diabetes had higher DII scores (overall weighted <i>p</i> < 0.001). Compared with low DII scores, participants with high DII scores were at a higher risk of long-term all-cause mortality (HR: 1.597, 95% CI: 1.370, 1.861; <i>p</i> < 0.001) and cardiovascular mortality (HR: 2.036, 95% CI: 1.458, 2.844; <i>p</i> < 0.001). The results were stable after adjusting for potential confounders. Moreover, the prognostic value of DII for long-term all-cause mortality existed only in diabetic individuals but not in the normoglycemia or prediabetes group (<i>p</i> for interaction = 0.006). In conclusion, compared to the normoglycemia or prediabetes groups, participants with diabetes had a higher DII score, which indicates a greater pro-inflammatory potential. Diabetic individuals with higher DII scores were at a higher risk of long-term all-cause and cardiovascular mortality. |
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| issn | 2072-6643 |
| language | English |
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| publishDate | 2022-06-01 |
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| spelling | doaj.art-80cebb5d934f4a4b8853d2c7dd90a6962023-12-01T21:37:51ZengMDPI AGNutrients2072-66432022-06-011413255610.3390/nu14132556Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic StatusSheng Yuan0Chenxi Song1Rui Zhang2Jining He3Kefei Dou4State Key Laboratory of Cardiovascular Disease, Beijing 102308, ChinaState Key Laboratory of Cardiovascular Disease, Beijing 102308, ChinaState Key Laboratory of Cardiovascular Disease, Beijing 102308, ChinaState Key Laboratory of Cardiovascular Disease, Beijing 102308, ChinaState Key Laboratory of Cardiovascular Disease, Beijing 102308, ChinaDietary inflammatory potential has been proven to be correlated with the incidence of diabetes and cardiovascular diseases. However, the evidence regarding the impact of dietary inflammatory patterns on long-term mortality is scarce. This cohort study aims to investigate the dietary inflammatory pattern of the general US individuals by baseline glycemic status and to estimate its association with long-term mortality. A total of 20,762 general American adults with different glycemic statuses from the National Health and Nutrition Examination Survey were included. We extracted 24-h dietary information, and the dietary inflammatory index (DII) was calculated. The outcomes were defined as 5-year all-cause and cardiovascular mortality. Compared with the normoglycemia group, individuals with prediabetes and type 2 diabetes had higher DII scores (overall weighted <i>p</i> < 0.001). Compared with low DII scores, participants with high DII scores were at a higher risk of long-term all-cause mortality (HR: 1.597, 95% CI: 1.370, 1.861; <i>p</i> < 0.001) and cardiovascular mortality (HR: 2.036, 95% CI: 1.458, 2.844; <i>p</i> < 0.001). The results were stable after adjusting for potential confounders. Moreover, the prognostic value of DII for long-term all-cause mortality existed only in diabetic individuals but not in the normoglycemia or prediabetes group (<i>p</i> for interaction = 0.006). In conclusion, compared to the normoglycemia or prediabetes groups, participants with diabetes had a higher DII score, which indicates a greater pro-inflammatory potential. Diabetic individuals with higher DII scores were at a higher risk of long-term all-cause and cardiovascular mortality.https://www.mdpi.com/2072-6643/14/13/2556diabetes mellitusprediabetesdietary inflammation indexnutritioninflammatory dietNHANES |
| spellingShingle | Sheng Yuan Chenxi Song Rui Zhang Jining He Kefei Dou Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status Nutrients diabetes mellitus prediabetes dietary inflammation index nutrition inflammatory diet NHANES |
| title | Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status |
| title_full | Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status |
| title_fullStr | Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status |
| title_full_unstemmed | Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status |
| title_short | Dietary Inflammation Index and Its Association with Long-Term All-Cause and Cardiovascular Mortality in the General US Population by Baseline Glycemic Status |
| title_sort | dietary inflammation index and its association with long term all cause and cardiovascular mortality in the general us population by baseline glycemic status |
| topic | diabetes mellitus prediabetes dietary inflammation index nutrition inflammatory diet NHANES |
| url | https://www.mdpi.com/2072-6643/14/13/2556 |
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