The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review

IntroductionDiabetes mellitus (DM) is a leading cause of morbidity and mortality worldwide. At the same time, digital health technologies (DHTs), which include mobile health apps (mHealth) have been rapidly gaining popularity in the self-management of chronic diseases, particularly following the COV...

Full description

Bibliographic Details
Main Authors: Sebastian Stevens, Susan Gallagher, Tim Andrews, Liz Ashall-Payne, Lloyd Humphreys, Simon Leigh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Clinical Diabetes and Healthcare
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcdhc.2022.936752/full
_version_ 1798030797244989440
author Sebastian Stevens
Sebastian Stevens
Susan Gallagher
Tim Andrews
Tim Andrews
Liz Ashall-Payne
Liz Ashall-Payne
Lloyd Humphreys
Simon Leigh
Simon Leigh
author_facet Sebastian Stevens
Sebastian Stevens
Susan Gallagher
Tim Andrews
Tim Andrews
Liz Ashall-Payne
Liz Ashall-Payne
Lloyd Humphreys
Simon Leigh
Simon Leigh
author_sort Sebastian Stevens
collection DOAJ
description IntroductionDiabetes mellitus (DM) is a leading cause of morbidity and mortality worldwide. At the same time, digital health technologies (DHTs), which include mobile health apps (mHealth) have been rapidly gaining popularity in the self-management of chronic diseases, particularly following the COVID-19 pandemic. However, while a great variety of DM-specific mHealth apps exist on the market, the evidence supporting their clinical effectiveness is still limited.MethodsA systematic review was performed. A systematic search was conducted in a major electronic database to identify randomized controlled trials (RCTs) of mHealth interventions in DM published between June 2010 and June 2020. The studies were categorized by the type of DM and impact of DM-specific mHealth apps on the management of glycated haemoglobin (HbA1c) was analysed.ResultsIn total, 25 studies comprising 3,360 patients were included. The methodological quality of included trials was mixed. Overall, participants diagnosed with T1DM, T2DM and Prediabetes all demonstrated greater improvements in HbA1c as a result of using a DHT compared with those who experienced usual care. The analysis revealed an overall improvement in HbA1c compared with usual care, with a mean difference of –0.56% for T1DM, –0.90% for T2DM and –0.26% for Prediabetes.ConclusionDM-specific mHealth apps may reduce HbA1c levels in patients with T1DM, T2DM and Prediabetes. The review highlights a need for further research on the wider clinical effectiveness of diabetes-specific mHealth specifically within T1DM and Prediabetes. These should include measures which go beyond HbA1c, capturing outcomes including short-term glycemic variability or hypoglycemic events.
first_indexed 2024-04-11T19:47:07Z
format Article
id doaj.art-80cf9768a1954a939b13f4d02fa9d922
institution Directory Open Access Journal
issn 2673-6616
language English
last_indexed 2024-04-11T19:47:07Z
publishDate 2022-10-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Clinical Diabetes and Healthcare
spelling doaj.art-80cf9768a1954a939b13f4d02fa9d9222022-12-22T04:06:27ZengFrontiers Media S.A.Frontiers in Clinical Diabetes and Healthcare2673-66162022-10-01310.3389/fcdhc.2022.936752936752The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic reviewSebastian Stevens0Sebastian Stevens1Susan Gallagher2Tim Andrews3Tim Andrews4Liz Ashall-Payne5Liz Ashall-Payne6Lloyd Humphreys7Simon Leigh8Simon Leigh9Research Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomCentre for Health Technology, University of Plymouth, Plymouth, United KingdomResearch Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomResearch Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomWarwick Medical School (WMS), The University of Warwick, Coventry, United KingdomResearch Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomWarwick Medical School (WMS), The University of Warwick, Coventry, United KingdomResearch Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomResearch Department, Organisation for the Review of Care and Health Applications, Daresbury, United KingdomWarwick Medical School (WMS), The University of Warwick, Coventry, United KingdomIntroductionDiabetes mellitus (DM) is a leading cause of morbidity and mortality worldwide. At the same time, digital health technologies (DHTs), which include mobile health apps (mHealth) have been rapidly gaining popularity in the self-management of chronic diseases, particularly following the COVID-19 pandemic. However, while a great variety of DM-specific mHealth apps exist on the market, the evidence supporting their clinical effectiveness is still limited.MethodsA systematic review was performed. A systematic search was conducted in a major electronic database to identify randomized controlled trials (RCTs) of mHealth interventions in DM published between June 2010 and June 2020. The studies were categorized by the type of DM and impact of DM-specific mHealth apps on the management of glycated haemoglobin (HbA1c) was analysed.ResultsIn total, 25 studies comprising 3,360 patients were included. The methodological quality of included trials was mixed. Overall, participants diagnosed with T1DM, T2DM and Prediabetes all demonstrated greater improvements in HbA1c as a result of using a DHT compared with those who experienced usual care. The analysis revealed an overall improvement in HbA1c compared with usual care, with a mean difference of –0.56% for T1DM, –0.90% for T2DM and –0.26% for Prediabetes.ConclusionDM-specific mHealth apps may reduce HbA1c levels in patients with T1DM, T2DM and Prediabetes. The review highlights a need for further research on the wider clinical effectiveness of diabetes-specific mHealth specifically within T1DM and Prediabetes. These should include measures which go beyond HbA1c, capturing outcomes including short-term glycemic variability or hypoglycemic events.https://www.frontiersin.org/articles/10.3389/fcdhc.2022.936752/fulldiabetes mellitusHbA1cglycemic controlmobile appsmhealth
spellingShingle Sebastian Stevens
Sebastian Stevens
Susan Gallagher
Tim Andrews
Tim Andrews
Liz Ashall-Payne
Liz Ashall-Payne
Lloyd Humphreys
Simon Leigh
Simon Leigh
The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
Frontiers in Clinical Diabetes and Healthcare
diabetes mellitus
HbA1c
glycemic control
mobile apps
mhealth
title The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
title_full The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
title_fullStr The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
title_full_unstemmed The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
title_short The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review
title_sort effectiveness of digital health technologies for patients with diabetes mellitus a systematic review
topic diabetes mellitus
HbA1c
glycemic control
mobile apps
mhealth
url https://www.frontiersin.org/articles/10.3389/fcdhc.2022.936752/full
work_keys_str_mv AT sebastianstevens theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT sebastianstevens theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT susangallagher theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT timandrews theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT timandrews theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lizashallpayne theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lizashallpayne theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lloydhumphreys theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT simonleigh theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT simonleigh theeffectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT sebastianstevens effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT sebastianstevens effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT susangallagher effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT timandrews effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT timandrews effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lizashallpayne effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lizashallpayne effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT lloydhumphreys effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT simonleigh effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview
AT simonleigh effectivenessofdigitalhealthtechnologiesforpatientswithdiabetesmellitusasystematicreview