Fibronectin Adsorption on Electrospun Synthetic Vascular Grafts Attracts Endothelial Progenitor Cells and Promotes Endothelialization in Dynamic In Vitro Culture

Fibronectin Adsorption on Electrospun Synthetic Vascular Grafts Attracts Endothelial Progenitor Cells and Promotes Endothelialization in Dynamic In Vitro Culture

Appropriate mechanical properties and fast endothelialization of synthetic grafts are key to ensure long-term functionality of implants. We used a newly developed biostable polyurethane elastomer (TPCU) to engineer electrospun vascular scaffolds with promising mechanical properties (E-modulus: 4.8 &...

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Bibliographic Details
Main Authors: Ruben Daum, Dmitri Visser, Constanze Wild, Larysa Kutuzova, Maria Schneider, Günter Lorenz, Martin Weiss, Svenja Hinderer, Ulrich A. Stock, Martina Seifert, Katja Schenke-Layland
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
vascular graft
endothelialization
tissue engineering
decorin
fibronectin
electrospinning
endothelial progenitor cells
bioreactor
biostable polyurethane
Online Access:https://www.mdpi.com/2073-4409/9/3/778

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