Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions
Abstract Cystic fibrosis (CF) is a genetic disease caused by a defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researchers have been exploring various aspects of the disease for almost 20 years. PubMed a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Mattioli 1885
2019-10-01
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| Series: | Multidisciplinary Respiratory Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40248-019-0193-4 |
| _version_ | 1827266436667539456 |
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| author | Samer Hammoudeh Wessam Gadelhak Atqah AbdulWahab Mona Al-Langawi Ibrahim A. Janahi |
| author_facet | Samer Hammoudeh Wessam Gadelhak Atqah AbdulWahab Mona Al-Langawi Ibrahim A. Janahi |
| author_sort | Samer Hammoudeh |
| collection | DOAJ |
| description | Abstract Cystic fibrosis (CF) is a genetic disease caused by a defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researchers have been exploring various aspects of the disease for almost 20 years. PubMed and Google Scholar were reviewed for articles related to CF in Qatar. The first publication appeared in the year 2000. Since then, several studies have been conducted on CF patients in Qatar considering a variety of topics. The presence of the CFTR I1234V mutation in a certain Arab tribe stands out as a distinguishing characteristic of CF patients in Qatar when compared to the larger Arab region or even worldwide. We aim here to summarize the existing CF research conducted in Qatar over the years as well as to introduce topics for future research. |
| first_indexed | 2024-03-07T17:56:54Z |
| format | Article |
| id | doaj.art-80d08dc24f7f467dac47e5673978a31b |
| institution | Directory Open Access Journal |
| issn | 2049-6958 |
| language | English |
| last_indexed | 2025-03-22T04:17:49Z |
| publishDate | 2019-10-01 |
| publisher | Mattioli 1885 |
| record_format | Article |
| series | Multidisciplinary Respiratory Medicine |
| spelling | doaj.art-80d08dc24f7f467dac47e5673978a31b2024-04-28T08:04:14ZengMattioli 1885Multidisciplinary Respiratory Medicine2049-69582019-10-011411610.1186/s40248-019-0193-4Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directionsSamer Hammoudeh0Wessam Gadelhak1Atqah AbdulWahab2Mona Al-Langawi3Ibrahim A. Janahi4Medical Research Center, Research Affairs, Hamad Medical CorporationMedical Research Center, Research Affairs, Hamad Medical CorporationPediatric Pulmonology, Pediatric Medicine, Sidra MedicineInternal Medicine, Hamad Medical CorporationPediatric Pulmonology, Pediatric Medicine, Sidra MedicineAbstract Cystic fibrosis (CF) is a genetic disease caused by a defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researchers have been exploring various aspects of the disease for almost 20 years. PubMed and Google Scholar were reviewed for articles related to CF in Qatar. The first publication appeared in the year 2000. Since then, several studies have been conducted on CF patients in Qatar considering a variety of topics. The presence of the CFTR I1234V mutation in a certain Arab tribe stands out as a distinguishing characteristic of CF patients in Qatar when compared to the larger Arab region or even worldwide. We aim here to summarize the existing CF research conducted in Qatar over the years as well as to introduce topics for future research.http://link.springer.com/article/10.1186/s40248-019-0193-4QatarCystic fibrosisCystic fibrosis transmembrane conductance regulatorCFTR I1234V mutationPancreatic sufficient |
| spellingShingle | Samer Hammoudeh Wessam Gadelhak Atqah AbdulWahab Mona Al-Langawi Ibrahim A. Janahi Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions Multidisciplinary Respiratory Medicine Qatar Cystic fibrosis Cystic fibrosis transmembrane conductance regulator CFTR I1234V mutation Pancreatic sufficient |
| title | Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions |
| title_full | Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions |
| title_fullStr | Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions |
| title_full_unstemmed | Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions |
| title_short | Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions |
| title_sort | approaching two decades of cystic fibrosis research in qatar a historical perspective and future directions |
| topic | Qatar Cystic fibrosis Cystic fibrosis transmembrane conductance regulator CFTR I1234V mutation Pancreatic sufficient |
| url | http://link.springer.com/article/10.1186/s40248-019-0193-4 |
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