COVID-19 and cardiovascular disease

Coronavirus disease 2019 (COVID-19), a spectrum of disease spanning from a barely symptomatic infection to critical illness, is caused by the new coronavirus - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although lung injury and acute respiratory distress syndrome have been at a ce...

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Bibliographic Details
Main Authors: Suri P, Arora V
Format: Article
Language:English
Published: KIMS Foundation and Research Center 2020-12-01
Series:Journal of Medical and Scientific Research
Subjects:
Online Access:http://jmsronline.com/article.aspx?ID=COVID-19-and-cardiovascular-disease
Description
Summary:Coronavirus disease 2019 (COVID-19), a spectrum of disease spanning from a barely symptomatic infection to critical illness, is caused by the new coronavirus - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although lung injury and acute respiratory distress syndrome have been at a centre stage as the most dreadful complications of COVID-19, the heart damage has recently emerged as yet another grim outcome in the virus’s repertoire of possible complications. The cardiac involvement occurs as a direct invasion of cardiomyocytes by the virus via the angiotensin‐converting enzyme 2 (ACE2) receptors and also indirectly by the inflammatory reaction due to cytokine storm. COVID-19 increases the severity of an already pre-existing heart disease and also unmasks the cardiac symptoms in a previously undiagnosed heart disease as well. Apart from this the drugs that are repurposed and are supposed to have a preventive or a therapeutic potential are also supposedly causing cardiac side effects. In the absence of substantial database all these seem to be a hypothetical correlation and one needs to rely on clinical skills and acumen.
ISSN:2321-1326
2394-112X