Ivermectin increases striatal cholinergic activity to facilitate dopamine terminal function

Ivermectin increases striatal cholinergic activity to facilitate dopamine terminal function

Abstract Ivermectin (IVM) is a commonly prescribed antiparasitic treatment with pharmacological effects on invertebrate glutamate ion channels resulting in paralysis and death of invertebrates. However, it can also act as a modulator of some vertebrate ion channels and has shown promise in facilitat...

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Bibliographic Details
Main Authors: Hillary A. Wadsworth, Alicia M. P. Warnecke, Joshua C. Barlow, J. Kayden Robinson, Emma Steimle, Joakim W. Ronström, Pacen E. Williams, Christopher J. Galbraith, Jared Baldridge, Michael W. Jakowec, Daryl L. Davies, Jordan T. Yorgason
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cell & Bioscience
Subjects:
Receptors
Purinergic P2X4 receptors
FSCV
Ivermectin
Parkinson’s
Online Access:https://doi.org/10.1186/s13578-024-01228-2

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