In vivo analysis of the role of O-glycosylations of von Willebrand factor.

The objective of this project was to study the function of O-glycosylations in von Willebrand factor (VWF) life cycle. In total, 14 different murine Vwf cDNAs mutated on one or several O-glycosylations sites were generated: 9 individual mutants, 2 doublets, 2 clusters and 1 mutant with all 9 murine...

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Bibliographic Details
Main Authors: Idinath Badirou, Mohamad Kurdi, Paulette Legendre, Julie Rayes, Marijke Bryckaert, Caterina Casari, Peter J Lenting, Olivier D Christophe, Cecile V Denis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22616016/pdf/?tool=EBI