IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolera...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/326 |
| _version_ | 1797198097054433280 |
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| author | A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova |
| author_facet | A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova |
| author_sort | A. L. Sizonenko |
| collection | DOAJ |
| description | Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα. |
| first_indexed | 2024-03-08T05:51:43Z |
| format | Article |
| id | doaj.art-80e0c0a4726548f188fe39c6192fb51e |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:54:26Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-80e0c0a4726548f188fe39c6192fb51e2024-04-22T13:07:35ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01112-328929210.15789/1563-0625-2009-2-3-289-292323IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIAA. L. Sizonenko0S. N. Beniova1M. P. Kostinov2E. V. Markelova3S. V. Taranova4Владивостокский Государственный медицинский университет, г. ВладивостокВладивостокский Государственный медицинский университет, г. ВладивостокНИИ вакцин и сывороток им. И.И. Мечникова, МоскваВладивостокский Государственный медицинский университет, г. ВладивостокВладивостокский Государственный медицинский университет, г. ВладивостокAbstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα.https://www.mimmun.ru/mimmun/article/view/326pneumococci infectionbacteriocarrierimmunitypneumo 23 |
| spellingShingle | A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA Медицинская иммунология pneumococci infection bacteriocarrier immunity pneumo 23 |
| title | IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
| title_full | IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
| title_fullStr | IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
| title_full_unstemmed | IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
| title_short | IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
| title_sort | immunological effect produced by vaccination with pneumo 23 of children with carriage of streptococcus pneumonia |
| topic | pneumococci infection bacteriocarrier immunity pneumo 23 |
| url | https://www.mimmun.ru/mimmun/article/view/326 |
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