Common and Rare Variants in Genes Associated with von Willebrand Factor Level Variation: No Accumulation of Rare Variants in Swedish von Willebrand Disease Patients

Common and Rare Variants in Genes Associated with von Willebrand Factor Level Variation: No Accumulation of Rare Variants in Swedish von Willebrand Disease Patients

Genome-wide association studies (GWASs) have identified genes that affect plasma von Willebrand factor (VWF) levels. ABO showed a strong effect, whereas smaller effects were seen for VWF, STXBP5, STAB2, SCARA5, STX2, TC2N, and CLEC4M. This study screened comprehensively for both common and rare vari...

Full description

Bibliographic Details
Main Authors: Eric Manderstedt, Christina Lind-Halldén, Stefan Lethagen, Christer Halldén
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2020-10-01
Series:TH Open
Subjects:
von willebrand factor
von willebrand disease
rare variant
dna sequencing
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1718885

Similar Items

Similar Items