PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS

Skin thicking simulating scleroderma is not rare in diabetes mellitus (about 2% among patients with diabetes mellitus), however it is not well known to rheumatologists and endocrinologists. The basis of the syndrome are the abnormalities of collagen and glycosaminoglycans metabolism accompanying by...

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Main Authors: T. A. Nevskaya, N. G. Gouseva
Format: Article
Language:Russian
Published: IMA PRESS LLC 2001-10-01
Series:Научно-практическая ревматология
Online Access:https://rsp.mediar-press.net/rsp/article/view/616
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author T. A. Nevskaya
N. G. Gouseva
author_facet T. A. Nevskaya
N. G. Gouseva
author_sort T. A. Nevskaya
collection DOAJ
description Skin thicking simulating scleroderma is not rare in diabetes mellitus (about 2% among patients with diabetes mellitus), however it is not well known to rheumatologists and endocrinologists. The basis of the syndrome are the abnormalities of collagen and glycosaminoglycans metabolism accompanying by the acid mucopolysaccharides accumulation in the deep part of the reticular dermis. Three cases of pseudosclerodrma in patients with long-standing complicated insulin-dependent diabetes mellitus are presented. The main clinical manifestations of pseudoscleroderma were marked cutaneous induration of the neck, body and proximal parts of extremities liked that of scleredema of Buschke ( 2 patients), and primary paraarticular induration leaded to the flexion contractures liked that of paraneoplastic scleroderma ( I patient). Possible mechanisms of development, clinical and morphological peculiarities and treatment for this syndrome are discussed.
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spelling doaj.art-80e6e95747334aef876a5359d9d949532023-03-22T13:45:37ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922001-10-01395798410.14412/1995-4484-2001-478556PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUST. A. NevskayaN. G. GousevaSkin thicking simulating scleroderma is not rare in diabetes mellitus (about 2% among patients with diabetes mellitus), however it is not well known to rheumatologists and endocrinologists. The basis of the syndrome are the abnormalities of collagen and glycosaminoglycans metabolism accompanying by the acid mucopolysaccharides accumulation in the deep part of the reticular dermis. Three cases of pseudosclerodrma in patients with long-standing complicated insulin-dependent diabetes mellitus are presented. The main clinical manifestations of pseudoscleroderma were marked cutaneous induration of the neck, body and proximal parts of extremities liked that of scleredema of Buschke ( 2 patients), and primary paraarticular induration leaded to the flexion contractures liked that of paraneoplastic scleroderma ( I patient). Possible mechanisms of development, clinical and morphological peculiarities and treatment for this syndrome are discussed.https://rsp.mediar-press.net/rsp/article/view/616
spellingShingle T. A. Nevskaya
N. G. Gouseva
PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
Научно-практическая ревматология
title PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
title_full PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
title_fullStr PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
title_full_unstemmed PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
title_short PSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUS
title_sort pseudosclerodermal syndrome in diabetes mellitus
url https://rsp.mediar-press.net/rsp/article/view/616
work_keys_str_mv AT tanevskaya pseudosclerodermalsyndromeindiabetesmellitus
AT nggouseva pseudosclerodermalsyndromeindiabetesmellitus