Anaerobic threshold using sweat lactate sensor under hypoxia
Abstract We aimed to investigate the reliability and validity of sweat lactate threshold (sLT) measurement based on the real-time monitoring of the transition in sweat lactate levels (sLA) under hypoxic exercise. In this cross-sectional study, 20 healthy participants who underwent exercise tests usi...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-49369-7 |
| _version_ | 1827399598842314752 |
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| author | Hiroki Okawara Yuji Iwasawa Tomonori Sawada Kazuhisa Sugai Kyohei Daigo Yuta Seki Genki Ichihara Daisuke Nakashima Motoaki Sano Masaya Nakamura Kazuki Sato Keiichi Fukuda Yoshinori Katsumata |
| author_facet | Hiroki Okawara Yuji Iwasawa Tomonori Sawada Kazuhisa Sugai Kyohei Daigo Yuta Seki Genki Ichihara Daisuke Nakashima Motoaki Sano Masaya Nakamura Kazuki Sato Keiichi Fukuda Yoshinori Katsumata |
| author_sort | Hiroki Okawara |
| collection | DOAJ |
| description | Abstract We aimed to investigate the reliability and validity of sweat lactate threshold (sLT) measurement based on the real-time monitoring of the transition in sweat lactate levels (sLA) under hypoxic exercise. In this cross-sectional study, 20 healthy participants who underwent exercise tests using respiratory gas analysis under hypoxia (fraction of inspired oxygen [FiO2], 15.4 ± 0.8%) in addition to normoxia (FiO2, 20.9%) were included; we simultaneously monitored sLA transition using a wearable lactate sensor. The initial significant elevation in sLA over the baseline was defined as sLT. Under hypoxia, real-time dynamic changes in sLA were successfully visualized, including a rapid, continual rise until volitionary exhaustion and a progressive reduction in the recovery phase. High intra- and inter-evaluator reliability was demonstrated for sLT’s repeat determinations (0.782 [0.607–0.898] and 0.933 [0.841–0.973]) as intraclass correlation coefficients [95% confidence interval]. sLT correlated with ventilatory threshold (VT) (r = 0.70, p < 0.01). A strong agreement was found in the Bland–Altman plot (mean difference/mean average time: − 15.5/550.8 s) under hypoxia. Our wearable device enabled continuous and real-time lactate assessment in sweat under hypoxic conditions in healthy participants with high reliability and validity, providing additional information to detect anaerobic thresholds in hypoxic conditions. |
| first_indexed | 2024-03-08T19:48:26Z |
| format | Article |
| id | doaj.art-80eacc753c3d48dfb664b97ba3b93b94 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T19:48:26Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-80eacc753c3d48dfb664b97ba3b93b942023-12-24T12:14:17ZengNature PortfolioScientific Reports2045-23222023-12-011311910.1038/s41598-023-49369-7Anaerobic threshold using sweat lactate sensor under hypoxiaHiroki Okawara0Yuji Iwasawa1Tomonori Sawada2Kazuhisa Sugai3Kyohei Daigo4Yuta Seki5Genki Ichihara6Daisuke Nakashima7Motoaki Sano8Masaya Nakamura9Kazuki Sato10Keiichi Fukuda11Yoshinori Katsumata12Department of Orthopaedic Surgery, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Orthopaedic Surgery, Keio University School of MedicineInstitute for Integrated Sports Medicine, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Orthopaedic Surgery, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Orthopaedic Surgery, Keio University School of MedicineInstitute for Integrated Sports Medicine, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineDepartment of Cardiology, Keio University School of MedicineAbstract We aimed to investigate the reliability and validity of sweat lactate threshold (sLT) measurement based on the real-time monitoring of the transition in sweat lactate levels (sLA) under hypoxic exercise. In this cross-sectional study, 20 healthy participants who underwent exercise tests using respiratory gas analysis under hypoxia (fraction of inspired oxygen [FiO2], 15.4 ± 0.8%) in addition to normoxia (FiO2, 20.9%) were included; we simultaneously monitored sLA transition using a wearable lactate sensor. The initial significant elevation in sLA over the baseline was defined as sLT. Under hypoxia, real-time dynamic changes in sLA were successfully visualized, including a rapid, continual rise until volitionary exhaustion and a progressive reduction in the recovery phase. High intra- and inter-evaluator reliability was demonstrated for sLT’s repeat determinations (0.782 [0.607–0.898] and 0.933 [0.841–0.973]) as intraclass correlation coefficients [95% confidence interval]. sLT correlated with ventilatory threshold (VT) (r = 0.70, p < 0.01). A strong agreement was found in the Bland–Altman plot (mean difference/mean average time: − 15.5/550.8 s) under hypoxia. Our wearable device enabled continuous and real-time lactate assessment in sweat under hypoxic conditions in healthy participants with high reliability and validity, providing additional information to detect anaerobic thresholds in hypoxic conditions.https://doi.org/10.1038/s41598-023-49369-7 |
| spellingShingle | Hiroki Okawara Yuji Iwasawa Tomonori Sawada Kazuhisa Sugai Kyohei Daigo Yuta Seki Genki Ichihara Daisuke Nakashima Motoaki Sano Masaya Nakamura Kazuki Sato Keiichi Fukuda Yoshinori Katsumata Anaerobic threshold using sweat lactate sensor under hypoxia Scientific Reports |
| title | Anaerobic threshold using sweat lactate sensor under hypoxia |
| title_full | Anaerobic threshold using sweat lactate sensor under hypoxia |
| title_fullStr | Anaerobic threshold using sweat lactate sensor under hypoxia |
| title_full_unstemmed | Anaerobic threshold using sweat lactate sensor under hypoxia |
| title_short | Anaerobic threshold using sweat lactate sensor under hypoxia |
| title_sort | anaerobic threshold using sweat lactate sensor under hypoxia |
| url | https://doi.org/10.1038/s41598-023-49369-7 |
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