Severe thrombocytopenia in a child with typhoid fever: a case report

Abstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admi...

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Main Authors: Mohammed Al Reesi, Glenn Stephens, Brendan McMullan
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13256-016-1138-6
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author Mohammed Al Reesi
Glenn Stephens
Brendan McMullan
author_facet Mohammed Al Reesi
Glenn Stephens
Brendan McMullan
author_sort Mohammed Al Reesi
collection DOAJ
description Abstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admitted with prolonged fever and found to have severe thrombocytopenia (platelets 16 × 109/L). Despite appropriate antibiotic therapy, his platelet recovery was slow, but did not lead to complications and he did not require platelet transfusion. Conclusions There is no consensus in the medical literature guiding the optimal management of severe thrombocytopenia in typhoid fever, but it may improve with conservative management, as in our case. The epidemiology and management of this condition merits further research to guide clinical practice.
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spelling doaj.art-80eafec20876422db6ffba87b0b353db2022-12-21T23:05:07ZengBMCJournal of Medical Case Reports1752-19472016-11-011011410.1186/s13256-016-1138-6Severe thrombocytopenia in a child with typhoid fever: a case reportMohammed Al Reesi0Glenn Stephens1Brendan McMullan2Sydney Children’s HospitalSydney Children’s HospitalSydney Children’s HospitalAbstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admitted with prolonged fever and found to have severe thrombocytopenia (platelets 16 × 109/L). Despite appropriate antibiotic therapy, his platelet recovery was slow, but did not lead to complications and he did not require platelet transfusion. Conclusions There is no consensus in the medical literature guiding the optimal management of severe thrombocytopenia in typhoid fever, but it may improve with conservative management, as in our case. The epidemiology and management of this condition merits further research to guide clinical practice.http://link.springer.com/article/10.1186/s13256-016-1138-6Typhoid feverThrombocytopeniaProlonged feverCase report
spellingShingle Mohammed Al Reesi
Glenn Stephens
Brendan McMullan
Severe thrombocytopenia in a child with typhoid fever: a case report
Journal of Medical Case Reports
Typhoid fever
Thrombocytopenia
Prolonged fever
Case report
title Severe thrombocytopenia in a child with typhoid fever: a case report
title_full Severe thrombocytopenia in a child with typhoid fever: a case report
title_fullStr Severe thrombocytopenia in a child with typhoid fever: a case report
title_full_unstemmed Severe thrombocytopenia in a child with typhoid fever: a case report
title_short Severe thrombocytopenia in a child with typhoid fever: a case report
title_sort severe thrombocytopenia in a child with typhoid fever a case report
topic Typhoid fever
Thrombocytopenia
Prolonged fever
Case report
url http://link.springer.com/article/10.1186/s13256-016-1138-6
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AT brendanmcmullan severethrombocytopeniainachildwithtyphoidfeveracasereport