Severe thrombocytopenia in a child with typhoid fever: a case report
Abstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admi...
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Format: | Article |
Language: | English |
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BMC
2016-11-01
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Series: | Journal of Medical Case Reports |
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Online Access: | http://link.springer.com/article/10.1186/s13256-016-1138-6 |
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author | Mohammed Al Reesi Glenn Stephens Brendan McMullan |
author_facet | Mohammed Al Reesi Glenn Stephens Brendan McMullan |
author_sort | Mohammed Al Reesi |
collection | DOAJ |
description | Abstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admitted with prolonged fever and found to have severe thrombocytopenia (platelets 16 × 109/L). Despite appropriate antibiotic therapy, his platelet recovery was slow, but did not lead to complications and he did not require platelet transfusion. Conclusions There is no consensus in the medical literature guiding the optimal management of severe thrombocytopenia in typhoid fever, but it may improve with conservative management, as in our case. The epidemiology and management of this condition merits further research to guide clinical practice. |
first_indexed | 2024-12-14T10:52:42Z |
format | Article |
id | doaj.art-80eafec20876422db6ffba87b0b353db |
institution | Directory Open Access Journal |
issn | 1752-1947 |
language | English |
last_indexed | 2024-12-14T10:52:42Z |
publishDate | 2016-11-01 |
publisher | BMC |
record_format | Article |
series | Journal of Medical Case Reports |
spelling | doaj.art-80eafec20876422db6ffba87b0b353db2022-12-21T23:05:07ZengBMCJournal of Medical Case Reports1752-19472016-11-011011410.1186/s13256-016-1138-6Severe thrombocytopenia in a child with typhoid fever: a case reportMohammed Al Reesi0Glenn Stephens1Brendan McMullan2Sydney Children’s HospitalSydney Children’s HospitalSydney Children’s HospitalAbstract Background Although thrombocytopenia is common in typhoid fever, its course, response to treatment, and need for specific therapies such as platelet transfusion are not well characterized. Case presentation We report a case of typhoid fever in a 4-year-old Asian male returned traveler, admitted with prolonged fever and found to have severe thrombocytopenia (platelets 16 × 109/L). Despite appropriate antibiotic therapy, his platelet recovery was slow, but did not lead to complications and he did not require platelet transfusion. Conclusions There is no consensus in the medical literature guiding the optimal management of severe thrombocytopenia in typhoid fever, but it may improve with conservative management, as in our case. The epidemiology and management of this condition merits further research to guide clinical practice.http://link.springer.com/article/10.1186/s13256-016-1138-6Typhoid feverThrombocytopeniaProlonged feverCase report |
spellingShingle | Mohammed Al Reesi Glenn Stephens Brendan McMullan Severe thrombocytopenia in a child with typhoid fever: a case report Journal of Medical Case Reports Typhoid fever Thrombocytopenia Prolonged fever Case report |
title | Severe thrombocytopenia in a child with typhoid fever: a case report |
title_full | Severe thrombocytopenia in a child with typhoid fever: a case report |
title_fullStr | Severe thrombocytopenia in a child with typhoid fever: a case report |
title_full_unstemmed | Severe thrombocytopenia in a child with typhoid fever: a case report |
title_short | Severe thrombocytopenia in a child with typhoid fever: a case report |
title_sort | severe thrombocytopenia in a child with typhoid fever a case report |
topic | Typhoid fever Thrombocytopenia Prolonged fever Case report |
url | http://link.springer.com/article/10.1186/s13256-016-1138-6 |
work_keys_str_mv | AT mohammedalreesi severethrombocytopeniainachildwithtyphoidfeveracasereport AT glennstephens severethrombocytopeniainachildwithtyphoidfeveracasereport AT brendanmcmullan severethrombocytopeniainachildwithtyphoidfeveracasereport |