Personality traits as risk factors for relapse or recurrence in major depression: a systematic review
BackgroundMajor depressive disorder (MDD) is highly recurrent. Identifying risk factors for relapse in depression is essential to improve prevention plans and therapeutic outcomes. Personality traits and personality disorders are widely considered to impact outcomes in MDD. We aimed to evaluate the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1176355/full |
| _version_ | 1797833199900950528 |
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| author | Nada Altaweel Nada Altaweel Rachel Upthegrove Rachel Upthegrove Andrew Surtees Andrew Surtees Buse Durdurak Steven Marwaha Steven Marwaha Steven Marwaha |
| author_facet | Nada Altaweel Nada Altaweel Rachel Upthegrove Rachel Upthegrove Andrew Surtees Andrew Surtees Buse Durdurak Steven Marwaha Steven Marwaha Steven Marwaha |
| author_sort | Nada Altaweel |
| collection | DOAJ |
| description | BackgroundMajor depressive disorder (MDD) is highly recurrent. Identifying risk factors for relapse in depression is essential to improve prevention plans and therapeutic outcomes. Personality traits and personality disorders are widely considered to impact outcomes in MDD. We aimed to evaluate the role of personality aspects in the risk of relapse and recurrence in MDD.MethodA PROSPERO-registered systematic review was conducted using Medline, Embase, PsycINFO, Web of Science and CINAHL as data sources, together with hand searching of four journals over the five years till 2022. There was independent abstract selection, quality assessment and data extraction from each study.ResultsTwenty two studies me t eligibility criteria involving 12,393 participants. Neurotic personality features are significantly associated with the risk of relapse and recurrence of depression, though the data is not uniform. There is some, though limited, evidence that borderline, obsessive-compulsive and dependent personality traits or disorders increase the risk for relapse in depression.LimitationsThe small number, in addition to the methodological heterogeneity of the included studies, did not allow further analysis, such as meta-analysis.ConclusionPeople with high neuroticism and dependent personality traits, borderline personality disorder or obsessive-compulsive personality disorder, compared to those without, may be at a higher risk of experiencing relapse or recurrence of MDD. Specific and targeted interventions may potentially reduce relapse and recurrence rates in these groups and could improve outcomes.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=235919, identifier: CRD42021235919. |
| first_indexed | 2024-04-09T14:19:38Z |
| format | Article |
| id | doaj.art-80ec449c9f53429bbc08fefaf6ea8de6 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-09T14:19:38Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-80ec449c9f53429bbc08fefaf6ea8de62023-05-05T04:29:22ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-05-011410.3389/fpsyt.2023.11763551176355Personality traits as risk factors for relapse or recurrence in major depression: a systematic reviewNada Altaweel0Nada Altaweel1Rachel Upthegrove2Rachel Upthegrove3Andrew Surtees4Andrew Surtees5Buse Durdurak6Steven Marwaha7Steven Marwaha8Steven Marwaha9School of Psychology, Institute for Mental Health, University of Birmingham, Birmingham, United KingdomDepartment of Psychology, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi ArabiaSchool of Psychology, Institute for Mental Health, University of Birmingham, Birmingham, United KingdomBirmingham Woman's and Children's NHS Foundation Trust, Birmingham, United KingdomSchool of Psychology, Institute for Mental Health, University of Birmingham, Birmingham, United KingdomBirmingham Woman's and Children's NHS Foundation Trust, Birmingham, United KingdomSchool of Psychology, Institute for Mental Health, University of Birmingham, Birmingham, United KingdomSchool of Psychology, Institute for Mental Health, University of Birmingham, Birmingham, United KingdomBirmingham Woman's and Children's NHS Foundation Trust, Birmingham, United KingdomSpecialist Mood Disorders Clinic, Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, United KingdomBackgroundMajor depressive disorder (MDD) is highly recurrent. Identifying risk factors for relapse in depression is essential to improve prevention plans and therapeutic outcomes. Personality traits and personality disorders are widely considered to impact outcomes in MDD. We aimed to evaluate the role of personality aspects in the risk of relapse and recurrence in MDD.MethodA PROSPERO-registered systematic review was conducted using Medline, Embase, PsycINFO, Web of Science and CINAHL as data sources, together with hand searching of four journals over the five years till 2022. There was independent abstract selection, quality assessment and data extraction from each study.ResultsTwenty two studies me t eligibility criteria involving 12,393 participants. Neurotic personality features are significantly associated with the risk of relapse and recurrence of depression, though the data is not uniform. There is some, though limited, evidence that borderline, obsessive-compulsive and dependent personality traits or disorders increase the risk for relapse in depression.LimitationsThe small number, in addition to the methodological heterogeneity of the included studies, did not allow further analysis, such as meta-analysis.ConclusionPeople with high neuroticism and dependent personality traits, borderline personality disorder or obsessive-compulsive personality disorder, compared to those without, may be at a higher risk of experiencing relapse or recurrence of MDD. Specific and targeted interventions may potentially reduce relapse and recurrence rates in these groups and could improve outcomes.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=235919, identifier: CRD42021235919.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1176355/fullpersonality traitsrelapserecurrencedepressionpersonality disorders |
| spellingShingle | Nada Altaweel Nada Altaweel Rachel Upthegrove Rachel Upthegrove Andrew Surtees Andrew Surtees Buse Durdurak Steven Marwaha Steven Marwaha Steven Marwaha Personality traits as risk factors for relapse or recurrence in major depression: a systematic review Frontiers in Psychiatry personality traits relapse recurrence depression personality disorders |
| title | Personality traits as risk factors for relapse or recurrence in major depression: a systematic review |
| title_full | Personality traits as risk factors for relapse or recurrence in major depression: a systematic review |
| title_fullStr | Personality traits as risk factors for relapse or recurrence in major depression: a systematic review |
| title_full_unstemmed | Personality traits as risk factors for relapse or recurrence in major depression: a systematic review |
| title_short | Personality traits as risk factors for relapse or recurrence in major depression: a systematic review |
| title_sort | personality traits as risk factors for relapse or recurrence in major depression a systematic review |
| topic | personality traits relapse recurrence depression personality disorders |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1176355/full |
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