<i>Codonopsis lanceolata</i> Extract Restores Smooth Muscle Vasorelaxation in Rat Carotid Arteries Even under High Extracellular K<sup>+</sup> Concentrations

<i>Codonopsis lanceolata</i> Extract Restores Smooth Muscle Vasorelaxation in Rat Carotid Arteries Even under High Extracellular K<sup>+</sup> Concentrations

Recent studies showed that <i>Codonopsis lanceolata</i> (CL) has antihypertensive effects. However, to date, no study has examined the effects of CL on vascular tone under a high extracellular K<sup>+</sup> concentration ([K<sup>+</sup>]<sub>o</sub>)....

Full description

Bibliographic Details
Main Authors:	Uihwan Kim, You Kyoung Shin, Jubin Park, Geun Hee Seol
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Series:	Nutrients
Subjects:	<i>Codonopsis lanceolata</i> endothelial dysfunction potassium vasorelaxation voltage-dependent Ca<sup>2+</sup> channel
Online Access:	https://www.mdpi.com/2072-6643/15/17/3791

Similar Items

Fermented Sprouts of <i>Codonopsis lanceolata</i> Suppress LPS-Induced Inflammatory Responses by Inhibiting NF-κB Signaling Pathway in RAW 264.7 Macrophages and CD1 Mice
by: Seung-Hyuk Choi, et al.
Published: (2023-06-01)

UPLC-QTOF-MS-Based Metabolomics and Antioxidant Capacity of <i>Codonopsis lanceolata</i> from Different Geographical Origins
by: Miso Nam, et al.
Published: (2023-01-01)

The complete chloroplast genome of Codonopsis lanceolata (Campanulaceae)
by: Junki Lee, et al.
Published: (2018-07-01)

De Novo Transcriptome Sequencing of <i>Codonopsis lanceolata</i> for Identification of Triterpene Synthase and Triterpene Acetyltransferase
by: Han-Bin Choi, et al.
Published: (2023-03-01)

Response of Bioactive Metabolite and Biosynthesis Related Genes to Methyl Jasmonate Elicitation in <i>Codonopsis pilosula</i>
by: Jiao-jiao Ji, et al.
Published: (2019-02-01)

The chromosome-level genome assembly of lance asiabell (Codonopsis lanceolata), a medicinal and vegetable plant of the Campanulaceae family
by: Woojong Jang, et al.
Published: (2023-02-01)

Vasorelaxant Activity of <i>Salvia hispanica</i> L.: Involvement of the Nitric Oxide Pathway in Its Pharmacological Mechanism
by: Luis A. Herbert-Doctor, et al.
Published: (2023-08-01)

Lancemaside A, a major triterpene saponin of Codonopsis lanceolata enhances regulation of nitric oxide synthesis via eNOS activation
by: Young Seok Lee, et al.
Published: (2019-05-01)

Oral hydrogel microspheres were used for highly specific delivery of Steamed Codonopsis lanceolata to exert the protective effects on cisplatin-induced acute kidney injury in mice
by: Yan-fei Li, et al.
Published: (2023-03-01)

Cracking the Endothelial Calcium (Ca<sup>2+</sup>) Code: A Matter of Timing and Spacing
by: Francesco Moccia, et al.
Published: (2023-11-01)

Embracing [XY<sub>3</sub>]<i><sup>m–</sup></i> and [XY<sub>4</sub>]<i><sup>m–</sup></i> Anions in Salts of [M(bpy)<sub>3</sub>]<i><sup>q</sup></i><sup>+</sup>
by: Edwin C. Constable, et al.
Published: (2023-01-01)

Influence of <i>Clear<sup>T</sup></i> and <i>Clear<sup>T2</sup></i> Agitation Conditions in the Fluorescence Imaging of 3D Spheroids
by: Daniel N. Silva, et al.
Published: (2020-12-01)

Safranal Induces Vasorelaxation by Inhibiting Ca<sup>2+</sup> Influx and Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Isolated Rat Aortic Rings
by: Noor Nadhim Al-Saigh, et al.
Published: (2022-06-01)

Associated Charmonium-Bottomonium Production in a Single Boson <i>e</i><sup>+</sup><i>e</i><sup>−</sup> Annihilation
by: Ilia Belov, et al.
Published: (2021-07-01)

Mycorrhizal Benefits of Salt-Stressed <i>Cinnamomum camphora</i> (L.) Presl. May Be Related to P and Mn<sup>2+</sup> Contents in Shoots, Biomass Allocation, and K<sup>+</sup>/Na<sup>+</sup> in Roots and Shoots
by: Yanhong Wang, et al.
Published: (2022-11-01)

Characterization of Two Na<sup>+</sup>(K<sup>+</sup>, Li<sup>+</sup>)/H<sup>+</sup> Antiporters from <i>Natronorubrum daqingense</i>
by: Qi Wang, et al.
Published: (2023-06-01)

Targeting PirA<i><sup>vp</sup></i> and PirB<i><sup>vp</sup></i> Toxins of <i>Vibrio parahaemolyticus</i> with Oilseed Peptides: An In Silico Approach
by: Joe-Hui Ong, et al.
Published: (2021-10-01)

The Effect of Decreased Ca<sup>++</sup>/Mg<sup>++</sup> ATPase Activity on <i>Lactobacillus delbrueckii</i> subsp. <i>bulgaricus</i> sp1.1 Survival during Spray Drying
by: Jialei Sun, et al.
Published: (2023-02-01)

Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer’s Disease Brain by Autoradiography Using [<sup>18</sup>F]Flotaza, [<sup>125</sup>I]IBETA, [<sup>124/125</sup>I]IPPI and Immunohistochemistry Analysis Using QuPath
by: Rommani Mondal, et al.
Published: (2023-03-01)

Protection and Safety Evaluation of Live Constructions Derived from the Pgm<sup>−</sup> and pPCP1<sup>−</sup> <i>Yersinia pestis</i> Strain
by: Xiuran Wang, et al.
Published: (2020-02-01)

Heterotridentate Organomonophosphines in Pt(κ<sup>3</sup>–X<sup>1</sup>P<sup>1</sup>X<sup>2</sup>)(Y) (X<sup>1,2</sup> = N<sup>1,2</sup> or S<sup>1,2</sup>), Pt(κ<sup>3</sup>–P<sup>1</sup>N<sup>1</sup>X<sup>1</sup>)(Y) (X<sup>1</sup> = O, C, S or Se) Pt(κ<sup>3</sup>–P<sup>1</sup>S<sup>1</sup>Cl<sup>1</sup>)(Cl) and Pt(κ<sup>3</sup>–P<sup>1</sup>Si<sup>1</sup>N<sup>1</sup>)(OL)—Structural Aspects
by: Milan Melník, et al.
Published: (2022-12-01)

Fixed Point Results in <i>C</i><sup>🟉</sup>-Algebra-Valued Partial <i>b</i>-Metric Spaces with Related Application
by: Gunaseelan Mani, et al.
Published: (2023-02-01)

Structural Insights to the Heterotetrameric Interaction between the <i>Vibrio parahaemolyticus</i> PirA<i><sup>vp</sup></i> and PirB<i><sup>vp</sup></i> Toxins and Activation of the Cry-Like Pore-Forming Domain
by: Shin-Jen Lin, et al.
Published: (2019-04-01)

A Functional K<sup>+</sup> Channel from Tetraselmis Virus 1, a Member of the <i>Mimiviridae</i>
by: Kerri Kukovetz, et al.
Published: (2020-09-01)

<i>G</i><sup>2</sup> Hermite Interpolation by Segmented Spirals
by: Yuxuan Zhou, et al.
Published: (2022-12-01)

Global Landscapes of the <i>Na<sup>+</sup>/H<sup>+</sup> Antiporter (NHX)</i> Family Members Uncover their Potential Roles in Regulating the Rapeseed Resistance to Salt Stress
by: Jia-qian Cui, et al.
Published: (2020-05-01)

Processing of Fluorescent Proteins May Prevent Detection of Prion Particles in [<i>PSI</i><sup>+</sup>] Cells
by: Andrew G. Matveenko, et al.
Published: (2022-11-01)

<i>Populus euphratica</i> Phospholipase Dδ Increases Salt Tolerance by Regulating K<sup>+</sup>/Na<sup>+</sup> and ROS Homeostasis in Arabidopsis
by: Ying Zhang, et al.
Published: (2022-04-01)

NH<sub>4</sub><sup>+</sup> Toxicity, Which Is Mainly Determined by the High NH<sub>4</sub><sup>+</sup>/K<sup>+</sup> Ratio, Is Alleviated by CIPK23 in <i>Arabidopsis</i>
by: Sujuan Shi, et al.
Published: (2020-04-01)

<i>GhNHX3D</i>, a Vacuolar-Localized Na<sup>+</sup>/H<sup>+</sup> Antiporter, Positively Regulates Salt Response in Upland Cotton
by: Junping Feng, et al.
Published: (2021-04-01)

Dirichlet Problem with <i>L</i><sup>1</sup>(<i>S</i>) Boundary Values
by: Alexander G. Ramm
Published: (2022-07-01)

Comparison of the Therapeutic Effects of [<sup>211</sup>At]NaAt and [<sup>131</sup>I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model
by: Tadashi Watabe, et al.
Published: (2022-08-01)

Depletion of Na<sup>+</sup>/H<sup>+</sup> Exchanger Isoform 1 Increases the Host Cell Resistance to <i>Trypanosoma cruzi</i> Invasion
by: João Paulo Ferreira Rodrigues, et al.
Published: (2022-11-01)

Phase I and II Clinical Trial Comparing the LBSap, Leishmune<sup>®</sup>, and Leish-Tec<sup>®</sup> Vaccines against Canine Visceral Leishmaniasis
by: Rodrigo Dian de Oliveira Aguiar-Soares, et al.
Published: (2020-11-01)

Screening of <i>Codonopsis radix</i> Polysaccharides with Different Molecular Weights and Evaluation of Their Immunomodulatory Activity In Vitro and In Vivo
by: Guangxin Li, et al.
Published: (2022-08-01)

The Mechanism and Role of <i>N</i><sup>6</sup>-Methyladenosine (m<sup>6</sup>A) Modification in Atherosclerosis and Atherosclerotic Diseases
by: Quandan Tan, et al.
Published: (2022-10-01)

The Organization of Pericentromeric Heterochromatin in Polytene Chromosome 3 of the <i>Drosophila</i> <i>melanogaster</i> Line with the <i>Rif1<sup>1</sup>; SuUR<sup>ES</sup> Su(var)3-9<sup>06</sup></i> Mutations Suppressing Underreplication
by: Tatyana Zykova, et al.
Published: (2021-10-01)

Spinach Plants Favor the Absorption of K<sup>+</sup> over Na<sup>+</sup> Regardless of Salinity, and May Benefit from Na<sup>+</sup> When K<sup>+</sup> is Deficient in the Soil
by: Jorge F. S. Ferreira, et al.
Published: (2020-04-01)

Ontogenetic Development of Gill and Na<sup>+</sup>/K<sup>+</sup> ATPase in the Air-Breathing Loach
by: Yaqiu Liu, et al.
Published: (2022-12-01)

Na<sup>+</sup>,K<sup>+</sup>-ATPase with Disrupted Na<sup>+</sup> Binding Sites I and III Binds Na<sup>+</sup> with Increased Affinity at Site II and Undergoes Na<sup>+</sup>-Activated Phosphorylation with ATP
by: Hang N. Nielsen, et al.
Published: (2024-01-01)