Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors
Background/Aims: Mucosal cutting biopsy (MCB) is useful for the histopathological diagnosis of gastric subepithelial tumors (SETs). However, there is little information on cases in which MCB did not establish a diagnosis. In the current study, we aimed to investigate the characteristics of cases in...
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2020-09-01
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| Series: | Clinical Endoscopy |
| Subjects: | |
| Online Access: | http://www.e-ce.org/upload/pdf/ce-2019-150.pdf |
| _version_ | 1797642650780696576 |
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| author | Yoshiko Nakano Toshitatsu Takao Yoshinori Morita Shinwa Tanaka Takashi Toyonaga Eiji Umegaki Yuzo Kodama |
| author_facet | Yoshiko Nakano Toshitatsu Takao Yoshinori Morita Shinwa Tanaka Takashi Toyonaga Eiji Umegaki Yuzo Kodama |
| author_sort | Yoshiko Nakano |
| collection | DOAJ |
| description | Background/Aims: Mucosal cutting biopsy (MCB) is useful for the histopathological diagnosis of gastric subepithelial tumors (SETs). However, there is little information on cases in which MCB did not establish a diagnosis. In the current study, we aimed to investigate the characteristics of cases in which MCB was unsuccessful. Methods: Cases in which MCB was used to histopathologically diagnose gastric SETs at Kobe University Hospital between August 2012 and October 2018 were retrospectively reviewed. Results: Forty-five cases in which MCB was used to diagnose 43 gastric SETs in 43 patients were analyzed. The median tumor size was 20 mm (range, 8–50 mm). Pathological examinations resulted in definitive and suspected diagnoses and no diagnosis in 29 (gastrointestinal stromal tumor: n=17, leiomyoma: n=7, aberrant pancreas: n=3, others: n=2), 6, and 10 cases, respectively. Failure to expose the tumor according to retrospective examinations of endoscopic images was significantly associated with no diagnosis. Other possible explanations included a less elevated tumor, biopsy of the surrounding field instead of the tumor due to the mobility, and poor endoscope maneuverability due to the tumor being close to the cardia. Conclusions: Clear exposure of gastric SETs during MCB may improve the diagnostic rate of such examinations. |
| first_indexed | 2024-03-11T14:03:22Z |
| format | Article |
| id | doaj.art-80ed3ce1b3384ecfbf7518aafcfae42d |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-11T14:03:22Z |
| publishDate | 2020-09-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-80ed3ce1b3384ecfbf7518aafcfae42d2023-11-02T03:39:52ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432020-09-0153557558210.5946/ce.2019.1507326Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial TumorsYoshiko Nakano0Toshitatsu Takao1Yoshinori Morita2Shinwa Tanaka3Takashi Toyonaga4Eiji Umegaki5Yuzo Kodama6 Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan Department of Endoscopy, Kobe University Hospital, Kobe, Japan Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, JapanBackground/Aims: Mucosal cutting biopsy (MCB) is useful for the histopathological diagnosis of gastric subepithelial tumors (SETs). However, there is little information on cases in which MCB did not establish a diagnosis. In the current study, we aimed to investigate the characteristics of cases in which MCB was unsuccessful. Methods: Cases in which MCB was used to histopathologically diagnose gastric SETs at Kobe University Hospital between August 2012 and October 2018 were retrospectively reviewed. Results: Forty-five cases in which MCB was used to diagnose 43 gastric SETs in 43 patients were analyzed. The median tumor size was 20 mm (range, 8–50 mm). Pathological examinations resulted in definitive and suspected diagnoses and no diagnosis in 29 (gastrointestinal stromal tumor: n=17, leiomyoma: n=7, aberrant pancreas: n=3, others: n=2), 6, and 10 cases, respectively. Failure to expose the tumor according to retrospective examinations of endoscopic images was significantly associated with no diagnosis. Other possible explanations included a less elevated tumor, biopsy of the surrounding field instead of the tumor due to the mobility, and poor endoscope maneuverability due to the tumor being close to the cardia. Conclusions: Clear exposure of gastric SETs during MCB may improve the diagnostic rate of such examinations.http://www.e-ce.org/upload/pdf/ce-2019-150.pdfgastric subepithelial tumorgastrointestinal stromal tumorsmucosal cutting biopsy |
| spellingShingle | Yoshiko Nakano Toshitatsu Takao Yoshinori Morita Shinwa Tanaka Takashi Toyonaga Eiji Umegaki Yuzo Kodama Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors Clinical Endoscopy gastric subepithelial tumor gastrointestinal stromal tumors mucosal cutting biopsy |
| title | Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors |
| title_full | Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors |
| title_fullStr | Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors |
| title_full_unstemmed | Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors |
| title_short | Reasons for Diagnostic Failure in Forty-Five Consecutive Mucosal Cutting Biopsy Examinations of Gastric Subepithelial Tumors |
| title_sort | reasons for diagnostic failure in forty five consecutive mucosal cutting biopsy examinations of gastric subepithelial tumors |
| topic | gastric subepithelial tumor gastrointestinal stromal tumors mucosal cutting biopsy |
| url | http://www.e-ce.org/upload/pdf/ce-2019-150.pdf |
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