| Summary: | Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or
low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a
47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year followup,
the nodules with large size and high 18F-fluorodeoxyglucose uptake in the initial study showed
progression with increasing sizes; however, most small nodules (size < 1 cm) demonstrated spontaneous
regression with peripheral rim or nodular calcification. The patient underwent surgical resection
for an enlarged nodule. Of note, it is unusual for an individual to have mixed progression
and regression concomitantly, which may be helpful in predicting the prognosis.
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