Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a 47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year followup, the nodules with l...

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Main Author: Ga Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng Park
Format: Article
Language:English
Published: The Korean Society of Radiology 2022-07-01
Series:대한영상의학회지
Online Access:https://doi.org/10.3348/jksr.2021.0135
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author Ga Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng Park
author_facet Ga Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng Park
author_sort Ga Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng Park
collection DOAJ
description Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a 47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year followup, the nodules with large size and high 18F-fluorodeoxyglucose uptake in the initial study showed progression with increasing sizes; however, most small nodules (size < 1 cm) demonstrated spontaneous regression with peripheral rim or nodular calcification. The patient underwent surgical resection for an enlarged nodule. Of note, it is unusual for an individual to have mixed progression and regression concomitantly, which may be helpful in predicting the prognosis.
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spelling doaj.art-80efc6452ab643f1a0932065c1b55d192022-12-22T00:58:09ZengThe Korean Society of Radiology대한영상의학회지2288-29282022-07-01834958964https://doi.org/10.3348/jksr.2021.0135Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging FindingsGa Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng ParkPulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a 47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year followup, the nodules with large size and high 18F-fluorodeoxyglucose uptake in the initial study showed progression with increasing sizes; however, most small nodules (size < 1 cm) demonstrated spontaneous regression with peripheral rim or nodular calcification. The patient underwent surgical resection for an enlarged nodule. Of note, it is unusual for an individual to have mixed progression and regression concomitantly, which may be helpful in predicting the prognosis.https://doi.org/10.3348/jksr.2021.0135
spellingShingle Ga Young Yi, Yoo Kyung Kim, Kwan Chang Kim, Heae Surng Park
Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
대한영상의학회지
title Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
title_full Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
title_fullStr Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
title_full_unstemmed Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
title_short Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
title_sort pulmonary multinodular epithelioid hemangioendothelioma with mixed progression and spontaneous regression during a 7 year follow up a case report and review of imaging findings
url https://doi.org/10.3348/jksr.2021.0135
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