Complement System Proteins in the Human Aqueous Humor and Their Association with Primary Open-Angle Glaucoma

Complement System Proteins in the Human Aqueous Humor and Their Association with Primary Open-Angle Glaucoma

This study discovers the complement protein profile in the aqueous humor (AH) of human subjects and investigates its association with primary open-angle glaucoma (POAG) pathogenesis. Among the 32 complement proteins identified, 22 were highly abundant and detected in more than 50% of AH samples. The...

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Bibliographic Details
Main Authors: Ayushi Vashishtha, Sharon W. Maina, Jeremy Altman, Garrett Jones, Tae Jin Lee, Kathryn E. Bollinger, Lane Ulrich, Marc Töteberg-Harms, Amy J. Estes, Wenbo Zhi, Shruti Sharma, Ashok Sharma
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Journal of Personalized Medicine
Subjects:
glaucoma
POAG
complement proteins
aqueous humor
proteomics
mass spectrometry
Online Access:https://www.mdpi.com/2075-4426/13/9/1400

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