Construction of PIK3C3 Transgenic Pig and Its Pathogenesis of Liver Damage
As a member of the PIKs family, PIK3C3 participates in autophagy and plays a central role in liver function. Several studies demonstrated that the complete suppression of PIK3C3 in mammals can cause hepatomegaly and hepatosteatosis. However, the function of PIK3C3 overexpression on the liver and oth...
Main Authors: | Jing Wang, Sami Ullah Khan, Pan Cao, Xi Chen, Fengchong Wang, Di Zou, Honghui Li, Heng Zhao, Kaixiang Xu, Deling Jiao, Chang Yang, Feiyan Zhu, Yaxuan Zhang, Yanhua Su, Wenmin Cheng, Baoyu Jia, Yubo Qing, Muhammad Ameen Jamal, Hong-Ye Zhao, Hong-Jiang Wei |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/12/5/630 |
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