Structure Determination of Felodipine Photoproducts in UV-Irradiated Medicines Using ESI-LC/MS/MS

Structure Determination of Felodipine Photoproducts in UV-Irradiated Medicines Using ESI-LC/MS/MS

Dihydropyridine drugs are well known as photodegradable pharmaceuticals. Herein, we evaluate the photostability of felodipine (FL) medicine (Splendil<sup>®</sup> (SPL) tablets) and its altered forms (powders and suspensions). FL is a type of dihydropyridine drug, but its photochemical be...

Full description

Bibliographic Details
Main Authors: Kohei Kawabata, Miya Kohashi, Shiori Akimoto, Hiroyuki Nishi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
felodipine
photodegradation
photodimerization
photooxidation
photoproduct
HPLC
Online Access:https://www.mdpi.com/1999-4923/15/2/697

Similar Items

Similar Items