Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction

Background: The intestinal tract is considered the body’s “engine” and the most impacted organ during sepsis. In this study, we explored toll-like receptor 4 (TLR4) functions in sepsis-induced intestinal barrier dysfunction. Methods: Wild-type and TLR4-knockout (KO) mice were used to establish a sep...

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Bibliographic Details
Main Authors: Lianghui Zhan, Jingru Zheng, Jianbiao Meng, Danting Fu, Lisha Pang, Chunlian Ji
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011672

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