Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction
Background: The intestinal tract is considered the body’s “engine” and the most impacted organ during sepsis. In this study, we explored toll-like receptor 4 (TLR4) functions in sepsis-induced intestinal barrier dysfunction. Methods: Wild-type and TLR4-knockout (KO) mice were used to establish a sep...
Main Authors: | Lianghui Zhan, Jingru Zheng, Jianbiao Meng, Danting Fu, Lisha Pang, Chunlian Ji |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222011672 |
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