New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em>
Chemical investigation of <em>Junceella juncea</em> has resulted in the isolation of three new briaranes designated juncenolides M–O (<strong>1</strong>–<strong>3</strong>). The structures of these compounds were det...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-06-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/10/6/1321 |
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| author | Tsong-Long Hwang Ya-Ching Shen Jiun-Yang Chang Ahmed Eid Fazary Chia-Ching Liaw |
| author_facet | Tsong-Long Hwang Ya-Ching Shen Jiun-Yang Chang Ahmed Eid Fazary Chia-Ching Liaw |
| author_sort | Tsong-Long Hwang |
| collection | DOAJ |
| description | Chemical investigation of <em>Junceella juncea</em> has resulted in the isolation of three new briaranes designated juncenolides M–O (<strong>1</strong>–<strong>3</strong>). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound <strong>1 </strong>is<strong> </strong>a<strong> </strong>new chlorinated briarane while compound <strong>3</strong> contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated. |
| first_indexed | 2024-04-13T00:36:45Z |
| format | Article |
| id | doaj.art-81119f2f7fe3450f85c0914e55f6e0d8 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-13T00:36:45Z |
| publishDate | 2012-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-81119f2f7fe3450f85c0914e55f6e0d82022-12-22T03:10:18ZengMDPI AGMarine Drugs1660-33972012-06-011061321133010.3390/md10061321New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em>Tsong-Long HwangYa-Ching ShenJiun-Yang ChangAhmed Eid FazaryChia-Ching LiawChemical investigation of <em>Junceella juncea</em> has resulted in the isolation of three new briaranes designated juncenolides M–O (<strong>1</strong>–<strong>3</strong>). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound <strong>1 </strong>is<strong> </strong>a<strong> </strong>new chlorinated briarane while compound <strong>3</strong> contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.http://www.mdpi.com/1660-3397/10/6/1321<em>Junceella juncea</em>briaranesanti-inflammatory activity |
| spellingShingle | Tsong-Long Hwang Ya-Ching Shen Jiun-Yang Chang Ahmed Eid Fazary Chia-Ching Liaw New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> Marine Drugs <em>Junceella juncea</em> briaranes anti-inflammatory activity |
| title | New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> |
| title_full | New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> |
| title_fullStr | New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> |
| title_full_unstemmed | New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> |
| title_short | New Briarane Diterpenoids from the Gorgonian Coral <em>Junceella juncea</em> |
| title_sort | new briarane diterpenoids from the gorgonian coral lt em gt junceella juncea lt em gt |
| topic | <em>Junceella juncea</em> briaranes anti-inflammatory activity |
| url | http://www.mdpi.com/1660-3397/10/6/1321 |
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