Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms

Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms

Interleukin (IL)-10 may have a therapeutic potential in atherosclerosis, but its mechanisms of action have not been clarified. Foam cell formation is a key event in atherogenesis, and apoptosis of these lipid-laden cells may promote plaque destabilization. We sought to explore whether IL-10 could ha...

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Bibliographic Details
Main Authors: Bente Halvorsen, Torgun Wæhre, Hanne Scholz, Ole Petter Clausen, Jan H. von der Thüsen, Fredrik Müller, Hilde Heimli, Serena Tonstad, Christian Hall, Stig S. Frøland, Erik A. Biessen, Jan Kristian Damås, Pål Aukrust
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Journal of Lipid Research
Subjects:
foam cell macrophages
acute coronary syndromes
atherosclerosis
apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340530

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