Ancient Bruises: a Case of Skin Lesions due to Vitamin C Deficiency

Scurvy was a common 18th century disease caused by vitamin C deficiency. It presents with multiple non-specific symptoms and can lead to capillary fragility due to impaired collagen synthesis. We report the case of a 63-year-old woman who presented with fatigue, nausea and progressive skin lesions c...

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Bibliographic Details
Main Authors: Dipti Rao, Roeland F. Stolk, Maaike H. de Blauw, Marcel M.C. Hovens, Robert-Jan Hassing
Format: Article
Language:English
Published: SMC MEDIA SRL 2015-10-01
Series:European Journal of Case Reports in Internal Medicine
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Online Access:http://ejcrim.com/index.php/EJCRIM/article/view/297
Description
Summary:Scurvy was a common 18th century disease caused by vitamin C deficiency. It presents with multiple non-specific symptoms and can lead to capillary fragility due to impaired collagen synthesis. We report the case of a 63-year-old woman who presented with fatigue, nausea and progressive skin lesions consisting of multiple ecchymoses on the legs as also described in the diary drawings of a navy doctor in the 19th century. The ascorbic acid level was undetectable low in the patient’s serum. However, treatment with 500 mg ascorbic acid daily dramatically improved the skin lesions within 5 days.
ISSN:2284-2594