The effect of calorie restriction on the anthropometric parameters, HOMA-IR index, and lipid profile of female office workers with overweight and obesity: a preliminary study
Objectives This study evaluates the effect of a 3-month calorie restriction (CR) without snacking on the anthropometric parameters, Homeostatic Model Assesment of Insulin Resistance (HOMA-IR), and lipid profiles of female office workers with overweight or obesity, whose physical activity was limited...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nofer Institute of Occupational Medicine
2022-07-01
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| Series: | International Journal of Occupational Medicine and Environmental Health |
| Subjects: | |
| Online Access: | http://ijomeh.eu/The-effect-of-calorie-restriction-on-the-anthropometric-parameters-HOMA-IR-index,150946,0,2.html |
| Summary: | Objectives
This study evaluates the effect of a 3-month calorie restriction (CR) without snacking on the anthropometric parameters, Homeostatic Model Assesment of Insulin Resistance (HOMA-IR), and lipid profiles of female office workers with overweight or obesity, whose physical activity was limited during the COVID-19 pandemic lockdown.
Material and Methods
Forty-eight women aged 20–38 years (28.9±5.24) with low physical
activity levels were divided into a non-snacking (NS) group (N = 21) and a snacking (S) group (N = 27) prior to the dietary intervention. Their daily
energy intake during the intervention was lowered by 30% compared with the baseline level, and the proportion of polyunsaturated fatty acids and
fiber in their diet was increased (to >30 g/day). The proportion of saturated fatty acids and simple carbohydrates was also reduced. The study participants
were assessed at the baseline and post-intervention for anthropometric variables (body weight, body fat percentage BMI, waist circumference,
hip circumference, waist-to-hip ratio) and the concentrations of insulin, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol
(LDL-C), and high-density lipoprotein cholesterol (HDL-C). Moreover, the values for HOMA-IR, the atherogenic index of plasma (AIP), and
the ratios of TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C were calculated.
Results
All anthropometric parameter values obtained post-intervention
were lower than the baseline in both groups. The serum insulin concentration and HOMA-IR decreased respectively by an average of 6% and 25%
in the NS group and 37% and 45% in the S group. The lipid profiles of all participants improved significantly, with the LDL-C concentration showing
a more promising trend in the S group (decrease by 27%) than in the NS group (17%).
Conclusions
The study showed that CR improved the anthropometric parameters, HOMA-IR index, and lipid profiles of all participants. Int J Occup Med Environ Health. 2022;35(6):693–706 |
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| ISSN: | 1232-1087 1896-494X |